Purpura Hemorrhagica

Laszlo M. Hunyadi, Nicola Pusterla

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

Equine purpura hemorrhagica (PH) is an acute, non-contagious, aseptic necrotizing vasculitis, characterized by edema and petechial or ecchymotic hemorrhage of the mucosa and subcutaneous tissue. The exact pathogenesis of PH is not fully understood at this time, but the vasculitis appears to be caused by the deposition of antigen-antibody immune complexes on blood vessel walls. Although the prevalence is unknown, PH is often associated with infection or vaccination against Streptococcus equi subsp. equi (S. equi). Purpura hemorrhagica can also occur with other infections, including equine influenza, equine viral arteritis, equine herpes virus type 1, Streptococcus equi subsp. zooepidemicus, Rhodococcus equi and Corynebacterium pseudotuberculosis. However, in some cases, the disease occurs in the absence of any known or documented infection. The mainstay treatment protocol for treating PH is aimed at reducing the inflammation associated with the blood vessel walls, removing the inciting cause, and providing supportive care.

Original languageEnglish (US)
Title of host publicationEquine Clinical Immunology
Publisherwiley
Pages83-86
Number of pages4
ISBN (Electronic)9781119086512
ISBN (Print)9781118558874
DOIs
StatePublished - Jan 5 2016

Fingerprint

Schoenlein-Henoch Purpura
Streptococcus equi
vasculitis
horses
blood vessels
Horses
Streptococcus equi subsp. equi
infection
Streptococcus equi subsp. zooepidemicus
arteritis
Corynebacterium pseudotuberculosis
equine influenza
Rhodococcus equi
Vasculitis
antigen-antibody complex
Antigen-Antibody Complex
Blood Vessels
Equine Arteritis Virus
edema
Infection

Keywords

  • Antigen-antibody immune complexes
  • Antigen-antibody immune complexes
  • Equine purpura hemorrhagica
  • Streptococcus equi

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Hunyadi, L. M., & Pusterla, N. (2016). Purpura Hemorrhagica. In Equine Clinical Immunology (pp. 83-86). wiley. https://doi.org/10.1002/9781119086512.ch10

Purpura Hemorrhagica. / Hunyadi, Laszlo M.; Pusterla, Nicola.

Equine Clinical Immunology. wiley, 2016. p. 83-86.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hunyadi, LM & Pusterla, N 2016, Purpura Hemorrhagica. in Equine Clinical Immunology. wiley, pp. 83-86. https://doi.org/10.1002/9781119086512.ch10
Hunyadi LM, Pusterla N. Purpura Hemorrhagica. In Equine Clinical Immunology. wiley. 2016. p. 83-86 https://doi.org/10.1002/9781119086512.ch10
Hunyadi, Laszlo M. ; Pusterla, Nicola. / Purpura Hemorrhagica. Equine Clinical Immunology. wiley, 2016. pp. 83-86
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