Purification and amino-terminal sequence analysis of the complement-fixing and precipitin antigens from Coccidioides immitis

S. Resnick, B. Zimmer, Demosthenes Pappagianis, A. Eakin, J. McKerrow

Research output: Contribution to journalArticle

12 Scopus citations


Two proteins (21 and 48 kilodaltons) purified from endospore-spherule culture filtrates of Coccidioides immitis are identified as precipitin and complement-fixing antigens, respectively. To allow specific structural comparison to antigens identified by other investigators and as a first step to eventual serodiagnostic antigen production by recombinant DNA technology, amino-terminal amino acid sequences were determined for these antigens.

Original languageEnglish (US)
Pages (from-to)385-388
Number of pages4
JournalJournal of Clinical Microbiology
Issue number2
StatePublished - 1990


ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

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