Pulmonary vascular biology during neonatal transition

Research output: Contribution to journalArticle

74 Citations (Scopus)

Abstract

Although the normal pulmonary vascular transition at birth takes place quickly in the delivery room, it has its basis in the complex structural and biochemical development of the lung. It is not surprising that this process can be easily disrupted by factors such as prematurity, intrauterine hypoxia, and parenchymal lung disease. The stimuli that initiate and maintain the transition are only beginning to be understood. Understanding the normal structure and function of the neonatal lung provides the foundation that will enable clinicians to enhance resuscitation to accomplish a normal transition in the delivery room.

Original languageEnglish (US)
Pages (from-to)601-619
Number of pages19
JournalClinics in Perinatology
Volume26
Issue number3
StatePublished - 1999
Externally publishedYes

Fingerprint

Delivery Rooms
Blood Vessels
Lung
Resuscitation
Lung Diseases
Parturition
Hypoxia

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Pulmonary vascular biology during neonatal transition. / Lakshminrusimha, Satyanarayana; Steinhorn, Robin H.

In: Clinics in Perinatology, Vol. 26, No. 3, 1999, p. 601-619.

Research output: Contribution to journalArticle

@article{54d9d4354ad64cef8dfcdca59eade497,
title = "Pulmonary vascular biology during neonatal transition",
abstract = "Although the normal pulmonary vascular transition at birth takes place quickly in the delivery room, it has its basis in the complex structural and biochemical development of the lung. It is not surprising that this process can be easily disrupted by factors such as prematurity, intrauterine hypoxia, and parenchymal lung disease. The stimuli that initiate and maintain the transition are only beginning to be understood. Understanding the normal structure and function of the neonatal lung provides the foundation that will enable clinicians to enhance resuscitation to accomplish a normal transition in the delivery room.",
author = "Satyanarayana Lakshminrusimha and Steinhorn, {Robin H}",
year = "1999",
language = "English (US)",
volume = "26",
pages = "601--619",
journal = "Clinics in Perinatology",
issn = "0095-5108",
publisher = "W.B. Saunders Ltd",
number = "3",

}

TY - JOUR

T1 - Pulmonary vascular biology during neonatal transition

AU - Lakshminrusimha, Satyanarayana

AU - Steinhorn, Robin H

PY - 1999

Y1 - 1999

N2 - Although the normal pulmonary vascular transition at birth takes place quickly in the delivery room, it has its basis in the complex structural and biochemical development of the lung. It is not surprising that this process can be easily disrupted by factors such as prematurity, intrauterine hypoxia, and parenchymal lung disease. The stimuli that initiate and maintain the transition are only beginning to be understood. Understanding the normal structure and function of the neonatal lung provides the foundation that will enable clinicians to enhance resuscitation to accomplish a normal transition in the delivery room.

AB - Although the normal pulmonary vascular transition at birth takes place quickly in the delivery room, it has its basis in the complex structural and biochemical development of the lung. It is not surprising that this process can be easily disrupted by factors such as prematurity, intrauterine hypoxia, and parenchymal lung disease. The stimuli that initiate and maintain the transition are only beginning to be understood. Understanding the normal structure and function of the neonatal lung provides the foundation that will enable clinicians to enhance resuscitation to accomplish a normal transition in the delivery room.

UR - http://www.scopus.com/inward/record.url?scp=0032792109&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032792109&partnerID=8YFLogxK

M3 - Article

C2 - 10494467

AN - SCOPUS:0032792109

VL - 26

SP - 601

EP - 619

JO - Clinics in Perinatology

JF - Clinics in Perinatology

SN - 0095-5108

IS - 3

ER -