Pulmonary involvement in adult-onset Still's disease

Gurtej S. Cheema, Francisco P. Quismorio

Research output: Contribution to journalArticlepeer-review

55 Scopus citations


Adult-onset Still's disease (AOSD) is a rare splenic disorder with an unknown cause. It is not uncommon for AOSD to involve other organs, such as the liver; the kidney; the bone marrow; and, less often, the lungs. In this review, we discuss the pulmonary complications of AOSD. Pulmonary involvement in AOSD usually consists of pleural effusion or transient pulmonary infiltrates, but it may become life threatening if it progresses to the adult respiratory distress syndrome. Chronic conditions, such as restrictive lung disease, have also been reported in patients with AOSD. The only treatment currently available is high-dose steroids, although other agents, such as intravenous immunoglobulin, cyclophosphamide, and azathioprine, have been tried with some success. Curr Opin Pulm Med 1999, 5:305-309

Original languageEnglish (US)
Pages (from-to)305-309
Number of pages5
JournalCurrent Opinion in Pulmonary Medicine
Issue number5
StatePublished - 1999
Externally publishedYes

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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