Abstract
Velocity-encoded cine magnetic resonance (MR) imaging provides two-dimensional velocity maps of a cross-sectional area of a vessel. Pulmonary flow and flow patterns in the main pulmonary artery were analyzed with velocity-encoded cine MR imaging and Doppler echocardiography in 10 patients with pulmonary hypertension (PH), one patient with a dilated main pulmonary artery, and 10 healthy subjects, and these findings were compared. Peak systolic velocity measured with velocity-encoded cine MR imaging was similar to that measured with Doppler echocardiography in healthy subjects and in patients with PH. Velocity-encoded cine MR imaging demonstrated substantial differences in velocity across the vascular lumen in PH. The flow pattern in healthy subjects was different than that in patients with PH; the latter had lower peak systolic velocity and greater retrograde flow after middle to late systole. The retrograde flow observed in patients with PH reflected hemodynamic events, since it was inversely proportional to pulmonary flow volume and directly proportional to pulmonary resistance and cross-sectional area of the vessel. Velocity-encoded cine MR imaging demonstrates an inhomogeneous flow profile in PH and may serve as a noninvasive method to estimate pulmonary vascular resistance.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 751-758 |
| Number of pages | 8 |
| Journal | Radiology |
| Volume | 183 |
| Issue number | 3 |
| State | Published - Jun 1992 |
| Externally published | Yes |
Fingerprint
Keywords
- Blood, flow dynamics, 60.919
- Hypertension, pulmonary, 58.78
- Lung, MR, 60.1214, 60.1296
- Lung, US, 60.1298, 60.12984
ASJC Scopus subject areas
- Radiological and Ultrasound Technology
Cite this
Pulmonary hypertension : Pulmonary flow guantification and flow profile analysis with velocity-encoded cine MR imaging. / Kondo, Chisato; Caputo, Gary R; Masui, Takayuki; Foster, Elyse; O'Sullivan, Margaret; Stulbarg, Michael S.; Golden, Jeff; Catterjee, Kanu; Higgins, Charles B.
In: Radiology, Vol. 183, No. 3, 06.1992, p. 751-758.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Pulmonary hypertension
T2 - Pulmonary flow guantification and flow profile analysis with velocity-encoded cine MR imaging
AU - Kondo, Chisato
AU - Caputo, Gary R
AU - Masui, Takayuki
AU - Foster, Elyse
AU - O'Sullivan, Margaret
AU - Stulbarg, Michael S.
AU - Golden, Jeff
AU - Catterjee, Kanu
AU - Higgins, Charles B.
PY - 1992/6
Y1 - 1992/6
N2 - Velocity-encoded cine magnetic resonance (MR) imaging provides two-dimensional velocity maps of a cross-sectional area of a vessel. Pulmonary flow and flow patterns in the main pulmonary artery were analyzed with velocity-encoded cine MR imaging and Doppler echocardiography in 10 patients with pulmonary hypertension (PH), one patient with a dilated main pulmonary artery, and 10 healthy subjects, and these findings were compared. Peak systolic velocity measured with velocity-encoded cine MR imaging was similar to that measured with Doppler echocardiography in healthy subjects and in patients with PH. Velocity-encoded cine MR imaging demonstrated substantial differences in velocity across the vascular lumen in PH. The flow pattern in healthy subjects was different than that in patients with PH; the latter had lower peak systolic velocity and greater retrograde flow after middle to late systole. The retrograde flow observed in patients with PH reflected hemodynamic events, since it was inversely proportional to pulmonary flow volume and directly proportional to pulmonary resistance and cross-sectional area of the vessel. Velocity-encoded cine MR imaging demonstrates an inhomogeneous flow profile in PH and may serve as a noninvasive method to estimate pulmonary vascular resistance.
AB - Velocity-encoded cine magnetic resonance (MR) imaging provides two-dimensional velocity maps of a cross-sectional area of a vessel. Pulmonary flow and flow patterns in the main pulmonary artery were analyzed with velocity-encoded cine MR imaging and Doppler echocardiography in 10 patients with pulmonary hypertension (PH), one patient with a dilated main pulmonary artery, and 10 healthy subjects, and these findings were compared. Peak systolic velocity measured with velocity-encoded cine MR imaging was similar to that measured with Doppler echocardiography in healthy subjects and in patients with PH. Velocity-encoded cine MR imaging demonstrated substantial differences in velocity across the vascular lumen in PH. The flow pattern in healthy subjects was different than that in patients with PH; the latter had lower peak systolic velocity and greater retrograde flow after middle to late systole. The retrograde flow observed in patients with PH reflected hemodynamic events, since it was inversely proportional to pulmonary flow volume and directly proportional to pulmonary resistance and cross-sectional area of the vessel. Velocity-encoded cine MR imaging demonstrates an inhomogeneous flow profile in PH and may serve as a noninvasive method to estimate pulmonary vascular resistance.
KW - Blood, flow dynamics, 60.919
KW - Hypertension, pulmonary, 58.78
KW - Lung, MR, 60.1214, 60.1296
KW - Lung, US, 60.1298, 60.12984
UR - http://www.scopus.com/inward/record.url?scp=0026691067&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026691067&partnerID=8YFLogxK
M3 - Article
VL - 183
SP - 751
EP - 758
JO - Radiology
JF - Radiology
SN - 0033-8419
IS - 3
ER -