Pulmonary hypertension

Pulmonary flow guantification and flow profile analysis with velocity-encoded cine MR imaging

Chisato Kondo, Gary R Caputo, Takayuki Masui, Elyse Foster, Margaret O'Sullivan, Michael S. Stulbarg, Jeff Golden, Kanu Catterjee, Charles B. Higgins

Research output: Contribution to journalArticle

135 Citations (Scopus)

Abstract

Velocity-encoded cine magnetic resonance (MR) imaging provides two-dimensional velocity maps of a cross-sectional area of a vessel. Pulmonary flow and flow patterns in the main pulmonary artery were analyzed with velocity-encoded cine MR imaging and Doppler echocardiography in 10 patients with pulmonary hypertension (PH), one patient with a dilated main pulmonary artery, and 10 healthy subjects, and these findings were compared. Peak systolic velocity measured with velocity-encoded cine MR imaging was similar to that measured with Doppler echocardiography in healthy subjects and in patients with PH. Velocity-encoded cine MR imaging demonstrated substantial differences in velocity across the vascular lumen in PH. The flow pattern in healthy subjects was different than that in patients with PH; the latter had lower peak systolic velocity and greater retrograde flow after middle to late systole. The retrograde flow observed in patients with PH reflected hemodynamic events, since it was inversely proportional to pulmonary flow volume and directly proportional to pulmonary resistance and cross-sectional area of the vessel. Velocity-encoded cine MR imaging demonstrates an inhomogeneous flow profile in PH and may serve as a noninvasive method to estimate pulmonary vascular resistance.

Original languageEnglish (US)
Pages (from-to)751-758
Number of pages8
JournalRadiology
Volume183
Issue number3
StatePublished - Jun 1992
Externally publishedYes

Fingerprint

Cine Magnetic Resonance Imaging
Pulmonary Hypertension
Lung
Healthy Volunteers
Doppler Echocardiography
Pulmonary Artery
Systole
Vascular Resistance
Blood Vessels
Hemodynamics

Keywords

  • Blood, flow dynamics, 60.919
  • Hypertension, pulmonary, 58.78
  • Lung, MR, 60.1214, 60.1296
  • Lung, US, 60.1298, 60.12984

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Kondo, C., Caputo, G. R., Masui, T., Foster, E., O'Sullivan, M., Stulbarg, M. S., ... Higgins, C. B. (1992). Pulmonary hypertension: Pulmonary flow guantification and flow profile analysis with velocity-encoded cine MR imaging. Radiology, 183(3), 751-758.

Pulmonary hypertension : Pulmonary flow guantification and flow profile analysis with velocity-encoded cine MR imaging. / Kondo, Chisato; Caputo, Gary R; Masui, Takayuki; Foster, Elyse; O'Sullivan, Margaret; Stulbarg, Michael S.; Golden, Jeff; Catterjee, Kanu; Higgins, Charles B.

In: Radiology, Vol. 183, No. 3, 06.1992, p. 751-758.

Research output: Contribution to journalArticle

Kondo, C, Caputo, GR, Masui, T, Foster, E, O'Sullivan, M, Stulbarg, MS, Golden, J, Catterjee, K & Higgins, CB 1992, 'Pulmonary hypertension: Pulmonary flow guantification and flow profile analysis with velocity-encoded cine MR imaging', Radiology, vol. 183, no. 3, pp. 751-758.
Kondo, Chisato ; Caputo, Gary R ; Masui, Takayuki ; Foster, Elyse ; O'Sullivan, Margaret ; Stulbarg, Michael S. ; Golden, Jeff ; Catterjee, Kanu ; Higgins, Charles B. / Pulmonary hypertension : Pulmonary flow guantification and flow profile analysis with velocity-encoded cine MR imaging. In: Radiology. 1992 ; Vol. 183, No. 3. pp. 751-758.
@article{3d0a368441eb4c3f8f19d691c2bd3d7c,
title = "Pulmonary hypertension: Pulmonary flow guantification and flow profile analysis with velocity-encoded cine MR imaging",
abstract = "Velocity-encoded cine magnetic resonance (MR) imaging provides two-dimensional velocity maps of a cross-sectional area of a vessel. Pulmonary flow and flow patterns in the main pulmonary artery were analyzed with velocity-encoded cine MR imaging and Doppler echocardiography in 10 patients with pulmonary hypertension (PH), one patient with a dilated main pulmonary artery, and 10 healthy subjects, and these findings were compared. Peak systolic velocity measured with velocity-encoded cine MR imaging was similar to that measured with Doppler echocardiography in healthy subjects and in patients with PH. Velocity-encoded cine MR imaging demonstrated substantial differences in velocity across the vascular lumen in PH. The flow pattern in healthy subjects was different than that in patients with PH; the latter had lower peak systolic velocity and greater retrograde flow after middle to late systole. The retrograde flow observed in patients with PH reflected hemodynamic events, since it was inversely proportional to pulmonary flow volume and directly proportional to pulmonary resistance and cross-sectional area of the vessel. Velocity-encoded cine MR imaging demonstrates an inhomogeneous flow profile in PH and may serve as a noninvasive method to estimate pulmonary vascular resistance.",
keywords = "Blood, flow dynamics, 60.919, Hypertension, pulmonary, 58.78, Lung, MR, 60.1214, 60.1296, Lung, US, 60.1298, 60.12984",
author = "Chisato Kondo and Caputo, {Gary R} and Takayuki Masui and Elyse Foster and Margaret O'Sullivan and Stulbarg, {Michael S.} and Jeff Golden and Kanu Catterjee and Higgins, {Charles B.}",
year = "1992",
month = "6",
language = "English (US)",
volume = "183",
pages = "751--758",
journal = "Radiology",
issn = "0033-8419",
publisher = "Radiological Society of North America Inc.",
number = "3",

}

TY - JOUR

T1 - Pulmonary hypertension

T2 - Pulmonary flow guantification and flow profile analysis with velocity-encoded cine MR imaging

AU - Kondo, Chisato

AU - Caputo, Gary R

AU - Masui, Takayuki

AU - Foster, Elyse

AU - O'Sullivan, Margaret

AU - Stulbarg, Michael S.

AU - Golden, Jeff

AU - Catterjee, Kanu

AU - Higgins, Charles B.

PY - 1992/6

Y1 - 1992/6

N2 - Velocity-encoded cine magnetic resonance (MR) imaging provides two-dimensional velocity maps of a cross-sectional area of a vessel. Pulmonary flow and flow patterns in the main pulmonary artery were analyzed with velocity-encoded cine MR imaging and Doppler echocardiography in 10 patients with pulmonary hypertension (PH), one patient with a dilated main pulmonary artery, and 10 healthy subjects, and these findings were compared. Peak systolic velocity measured with velocity-encoded cine MR imaging was similar to that measured with Doppler echocardiography in healthy subjects and in patients with PH. Velocity-encoded cine MR imaging demonstrated substantial differences in velocity across the vascular lumen in PH. The flow pattern in healthy subjects was different than that in patients with PH; the latter had lower peak systolic velocity and greater retrograde flow after middle to late systole. The retrograde flow observed in patients with PH reflected hemodynamic events, since it was inversely proportional to pulmonary flow volume and directly proportional to pulmonary resistance and cross-sectional area of the vessel. Velocity-encoded cine MR imaging demonstrates an inhomogeneous flow profile in PH and may serve as a noninvasive method to estimate pulmonary vascular resistance.

AB - Velocity-encoded cine magnetic resonance (MR) imaging provides two-dimensional velocity maps of a cross-sectional area of a vessel. Pulmonary flow and flow patterns in the main pulmonary artery were analyzed with velocity-encoded cine MR imaging and Doppler echocardiography in 10 patients with pulmonary hypertension (PH), one patient with a dilated main pulmonary artery, and 10 healthy subjects, and these findings were compared. Peak systolic velocity measured with velocity-encoded cine MR imaging was similar to that measured with Doppler echocardiography in healthy subjects and in patients with PH. Velocity-encoded cine MR imaging demonstrated substantial differences in velocity across the vascular lumen in PH. The flow pattern in healthy subjects was different than that in patients with PH; the latter had lower peak systolic velocity and greater retrograde flow after middle to late systole. The retrograde flow observed in patients with PH reflected hemodynamic events, since it was inversely proportional to pulmonary flow volume and directly proportional to pulmonary resistance and cross-sectional area of the vessel. Velocity-encoded cine MR imaging demonstrates an inhomogeneous flow profile in PH and may serve as a noninvasive method to estimate pulmonary vascular resistance.

KW - Blood, flow dynamics, 60.919

KW - Hypertension, pulmonary, 58.78

KW - Lung, MR, 60.1214, 60.1296

KW - Lung, US, 60.1298, 60.12984

UR - http://www.scopus.com/inward/record.url?scp=0026691067&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026691067&partnerID=8YFLogxK

M3 - Article

VL - 183

SP - 751

EP - 758

JO - Radiology

JF - Radiology

SN - 0033-8419

IS - 3

ER -