Pulmonary disease in liver transplant recipients: Spectrum of CT features

Friedrich D Knollmann, J. Mäurer, W. O. Bechstein, T. J. Vogl, P. Neuhaus, R. Felix

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Purpose: To determine the features of pulmonary disease in liver transplant recipients by CT. Material and Methods: Of 792 patients, 102 were referred to thoracic CT 3-2093 days after the transplantation procedure (median 107 days). All CT studies were retrospectively analyzed and correlated with clinical, microbiological, serological and histopathological findings. Results: Eighty-eight of 102 patients (86%) had an abnormal CT. In 25 patients (25%), an elevated right hemidiaphragm, basal atelectasis and small effusions were the only abnormalities. Fourty-one patients (40%) displayed an infiltrate and 13 (13%) a mass lesion. Evidence of cytomegalovirus (CMV) infection was found in 20 patients. CMV pneumonia was suggested by an interstitial pattern of pneumonia on CT (n=13). Pneumocystis carinii pneumonia was high-lighted by peribronchovascular infiltrates (n=5/8), bacterial pneumonia (n=24) including legionellosis (n=13) by bilateral effusions (n=14) and lobar consolidation (n=13). In 7/41 patients (17%) with both clinically apparent pulmonary disease and CT signs of pneumonia, no pathogen could be detected. Neoplastic disease was mostly due to tumor recurrence (n=6). Conclusion: Thoracic CT of liver transplant recipients aids in detecting and classifying both infectious and neoplastic complications.

Original languageEnglish (US)
Pages (from-to)230-236
Number of pages7
JournalActa Radiologica
Volume41
Issue number3
StatePublished - May 2000
Externally publishedYes

Keywords

  • Clinical effectiveness
  • Liver, transplantation
  • Lung diseases, CT

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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  • Cite this

    Knollmann, F. D., Mäurer, J., Bechstein, W. O., Vogl, T. J., Neuhaus, P., & Felix, R. (2000). Pulmonary disease in liver transplant recipients: Spectrum of CT features. Acta Radiologica, 41(3), 230-236.