Pulmonary disease in liver transplant recipients: Spectrum of CT features

Friedrich D Knollmann, J. Mäurer, W. O. Bechstein, T. J. Vogl, P. Neuhaus, R. Felix

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Purpose: To determine the features of pulmonary disease in liver transplant recipients by CT. Material and Methods: Of 792 patients, 102 were referred to thoracic CT 3-2093 days after the transplantation procedure (median 107 days). All CT studies were retrospectively analyzed and correlated with clinical, microbiological, serological and histopathological findings. Results: Eighty-eight of 102 patients (86%) had an abnormal CT. In 25 patients (25%), an elevated right hemidiaphragm, basal atelectasis and small effusions were the only abnormalities. Fourty-one patients (40%) displayed an infiltrate and 13 (13%) a mass lesion. Evidence of cytomegalovirus (CMV) infection was found in 20 patients. CMV pneumonia was suggested by an interstitial pattern of pneumonia on CT (n=13). Pneumocystis carinii pneumonia was high-lighted by peribronchovascular infiltrates (n=5/8), bacterial pneumonia (n=24) including legionellosis (n=13) by bilateral effusions (n=14) and lobar consolidation (n=13). In 7/41 patients (17%) with both clinically apparent pulmonary disease and CT signs of pneumonia, no pathogen could be detected. Neoplastic disease was mostly due to tumor recurrence (n=6). Conclusion: Thoracic CT of liver transplant recipients aids in detecting and classifying both infectious and neoplastic complications.

Original languageEnglish (US)
Pages (from-to)230-236
Number of pages7
JournalActa Radiologica
Volume41
Issue number3
StatePublished - May 2000
Externally publishedYes

Fingerprint

Lung Diseases
Liver
Pneumonia
Thorax
Legionellosis
Bacterial Pneumonia
Pneumocystis Pneumonia
Pulmonary Atelectasis
Interstitial Lung Diseases
Cytomegalovirus Infections
Cytomegalovirus
Transplant Recipients
Transplantation
Recurrence
Neoplasms

Keywords

  • Clinical effectiveness
  • Liver, transplantation
  • Lung diseases, CT

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Knollmann, F. D., Mäurer, J., Bechstein, W. O., Vogl, T. J., Neuhaus, P., & Felix, R. (2000). Pulmonary disease in liver transplant recipients: Spectrum of CT features. Acta Radiologica, 41(3), 230-236.

Pulmonary disease in liver transplant recipients : Spectrum of CT features. / Knollmann, Friedrich D; Mäurer, J.; Bechstein, W. O.; Vogl, T. J.; Neuhaus, P.; Felix, R.

In: Acta Radiologica, Vol. 41, No. 3, 05.2000, p. 230-236.

Research output: Contribution to journalArticle

Knollmann, FD, Mäurer, J, Bechstein, WO, Vogl, TJ, Neuhaus, P & Felix, R 2000, 'Pulmonary disease in liver transplant recipients: Spectrum of CT features', Acta Radiologica, vol. 41, no. 3, pp. 230-236.
Knollmann FD, Mäurer J, Bechstein WO, Vogl TJ, Neuhaus P, Felix R. Pulmonary disease in liver transplant recipients: Spectrum of CT features. Acta Radiologica. 2000 May;41(3):230-236.
Knollmann, Friedrich D ; Mäurer, J. ; Bechstein, W. O. ; Vogl, T. J. ; Neuhaus, P. ; Felix, R. / Pulmonary disease in liver transplant recipients : Spectrum of CT features. In: Acta Radiologica. 2000 ; Vol. 41, No. 3. pp. 230-236.
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