Pulmonary alveolar macrophage

Demonstration of Na+ - K+, Mg++ ATPase activity

Mohammad G. Mustafa, Ali B. Ibrahim, Chinh T. Le, Carroll E Cross

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Pulmonary alveolar macrophages (PAMs) were isolated from the lungs of rabbits and sheep. The intact cells manifested an ATPase activity which was dependent upon the presence of Mg++ and was further stimulated upon addition of Na+ and K+. Cardiac glycosides strongly inhibited the system. The activity was somewhat sensitive to azide, Ca++ and Cd++ but insensitive to dinitrophenol and oligomycin. It is possible that environmental agents may influence this PAM Na+ - K+, Mg++ ATPase.

Original languageEnglish (US)
Pages (from-to)1343-1351
Number of pages9
JournalLife Sciences
Volume8
Issue number24 PART 2
StatePublished - Dec 15 1969

Fingerprint

Alveolar Macrophages
Demonstrations
Dinitrophenols
Oligomycins
Cardiac Glycosides
Azides
Adenosine Triphosphatases
Sheep
Rabbits
Lung
magnesium sodium potassium ATPase

ASJC Scopus subject areas

  • Pharmacology

Cite this

Mustafa, M. G., Ibrahim, A. B., Le, C. T., & Cross, C. E. (1969). Pulmonary alveolar macrophage: Demonstration of Na+ - K+, Mg++ ATPase activity. Life Sciences, 8(24 PART 2), 1343-1351.

Pulmonary alveolar macrophage : Demonstration of Na+ - K+, Mg++ ATPase activity. / Mustafa, Mohammad G.; Ibrahim, Ali B.; Le, Chinh T.; Cross, Carroll E.

In: Life Sciences, Vol. 8, No. 24 PART 2, 15.12.1969, p. 1343-1351.

Research output: Contribution to journalArticle

Mustafa, MG, Ibrahim, AB, Le, CT & Cross, CE 1969, 'Pulmonary alveolar macrophage: Demonstration of Na+ - K+, Mg++ ATPase activity', Life Sciences, vol. 8, no. 24 PART 2, pp. 1343-1351.
Mustafa MG, Ibrahim AB, Le CT, Cross CE. Pulmonary alveolar macrophage: Demonstration of Na+ - K+, Mg++ ATPase activity. Life Sciences. 1969 Dec 15;8(24 PART 2):1343-1351.
Mustafa, Mohammad G. ; Ibrahim, Ali B. ; Le, Chinh T. ; Cross, Carroll E. / Pulmonary alveolar macrophage : Demonstration of Na+ - K+, Mg++ ATPase activity. In: Life Sciences. 1969 ; Vol. 8, No. 24 PART 2. pp. 1343-1351.
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