Pulmonary alveolar macrophages (PAMs) were isolated from the lungs of rabbits and sheep. The intact cells manifested an ATPase activity which was dependent upon the presence of Mg++ and was further stimulated upon addition of Na+ and K+. Cardiac glycosides strongly inhibited the system. The activity was somewhat sensitive to azide, Ca++ and Cd++ but insensitive to dinitrophenol and oligomycin. It is possible that environmental agents may influence this PAM Na+ - K+, Mg++ ATPase.
|Original language||English (US)|
|Number of pages||9|
|Issue number||24 PART 2|
|State||Published - Dec 15 1969|
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