Psychometrically matched measures of global cognition, memory, and executive function for assessment of cognitive decline in older persons

Dan Mungas, Bruce R. Reed, Joel H. Kramer

Research output: Contribution to journalArticle

81 Scopus citations

Abstract

Item response theory methods were used to derive psychometrically sophisticated measures of global cognition, memory, and executive function. Goals were that these measures (a) could be derived from commonly used neuropsychological tests, (b) would have linear measurement properties, and (c) would be psychometrically matched. Scale development was based on a sample of 400 older individuals with cognitive function ranging from normal to demented. Scales were reasonably matched with linear measurement over an ability range relevant to many important clinical applications. Cognitively normal, mild impairment, and dementia participant groups differed on baseline measures and rate of decline. Association of measures with quantitative structural magnetic resonance imaging variables followed expected patterns. This approach to scale development may have applications for other neuropsychological assessment problems.

Original languageEnglish (US)
Pages (from-to)380-392
Number of pages13
JournalNeuropsychology
Volume17
Issue number3
DOIs
StatePublished - Jul 2003

ASJC Scopus subject areas

  • Biological Psychiatry
  • Neuropsychology and Physiological Psychology

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