Abstract
The primary aim of the present study was to assess the prevalence of psychiatric comorbidity in a large sample of methamphetamine (MA)-dependent subjects using a validated structured clinical interview, without limitation to sexual orientation or participation in a treatment program. The secondary aim was to assess whether the prevalence of psychiatric comorbidities varied by gender. Structured clinical interviews (SCIDs) were administered to 189 MA-dependent subjects and lifetime prevalence of DSM-IV diagnoses was assessed. Across the sample, 28.6% had primary psychotic disorders, 23.8% of which were substance-induced; 13.2% had MA-induced delusional disorders and 11.1% had MA-induced hallucinations. A substantial number of lifetime mood disorders were identified that were not substance-induced (32.3%), whereas 14.8% had mood disorders induced by substances, and 10.6% had mood disorders induced by amphetamines. Of all participants, 26.5% had anxiety disorders and 3.7% had a substance-induced anxiety disorder, all of which were induced by MA. Male subjects reported a higher percentage of MA-induced delusions compared to female abusers. Given the impact of MA psychosis and other drug-induced symptoms on hospitals and mental health services, the description and characterization of comorbid psychiatric symptoms associated with MA use is of paramount importance.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 356-361 |
| Number of pages | 6 |
| Journal | Psychiatry Research |
| Volume | 186 |
| Issue number | 2-3 |
| DOIs | |
| State | Published - Apr 30 2011 |
Fingerprint
Keywords
- Gender
- Psychiatric comorbidity
- Stimulants
- Substance abuse
ASJC Scopus subject areas
- Psychiatry and Mental health
- Biological Psychiatry
Cite this
Psychiatric comorbidity in methamphetamine dependence. / Salo, Ruth; Flower, Keith; Kielstein, Anousheh; Leamon, Martin H; Nordahl, Thomas E; Galloway, Gantt P.
In: Psychiatry Research, Vol. 186, No. 2-3, 30.04.2011, p. 356-361.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Psychiatric comorbidity in methamphetamine dependence
AU - Salo, Ruth
AU - Flower, Keith
AU - Kielstein, Anousheh
AU - Leamon, Martin H
AU - Nordahl, Thomas E
AU - Galloway, Gantt P.
PY - 2011/4/30
Y1 - 2011/4/30
N2 - The primary aim of the present study was to assess the prevalence of psychiatric comorbidity in a large sample of methamphetamine (MA)-dependent subjects using a validated structured clinical interview, without limitation to sexual orientation or participation in a treatment program. The secondary aim was to assess whether the prevalence of psychiatric comorbidities varied by gender. Structured clinical interviews (SCIDs) were administered to 189 MA-dependent subjects and lifetime prevalence of DSM-IV diagnoses was assessed. Across the sample, 28.6% had primary psychotic disorders, 23.8% of which were substance-induced; 13.2% had MA-induced delusional disorders and 11.1% had MA-induced hallucinations. A substantial number of lifetime mood disorders were identified that were not substance-induced (32.3%), whereas 14.8% had mood disorders induced by substances, and 10.6% had mood disorders induced by amphetamines. Of all participants, 26.5% had anxiety disorders and 3.7% had a substance-induced anxiety disorder, all of which were induced by MA. Male subjects reported a higher percentage of MA-induced delusions compared to female abusers. Given the impact of MA psychosis and other drug-induced symptoms on hospitals and mental health services, the description and characterization of comorbid psychiatric symptoms associated with MA use is of paramount importance.
AB - The primary aim of the present study was to assess the prevalence of psychiatric comorbidity in a large sample of methamphetamine (MA)-dependent subjects using a validated structured clinical interview, without limitation to sexual orientation or participation in a treatment program. The secondary aim was to assess whether the prevalence of psychiatric comorbidities varied by gender. Structured clinical interviews (SCIDs) were administered to 189 MA-dependent subjects and lifetime prevalence of DSM-IV diagnoses was assessed. Across the sample, 28.6% had primary psychotic disorders, 23.8% of which were substance-induced; 13.2% had MA-induced delusional disorders and 11.1% had MA-induced hallucinations. A substantial number of lifetime mood disorders were identified that were not substance-induced (32.3%), whereas 14.8% had mood disorders induced by substances, and 10.6% had mood disorders induced by amphetamines. Of all participants, 26.5% had anxiety disorders and 3.7% had a substance-induced anxiety disorder, all of which were induced by MA. Male subjects reported a higher percentage of MA-induced delusions compared to female abusers. Given the impact of MA psychosis and other drug-induced symptoms on hospitals and mental health services, the description and characterization of comorbid psychiatric symptoms associated with MA use is of paramount importance.
KW - Gender
KW - Psychiatric comorbidity
KW - Stimulants
KW - Substance abuse
UR - http://www.scopus.com/inward/record.url?scp=79952359698&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79952359698&partnerID=8YFLogxK
U2 - 10.1016/j.psychres.2010.09.014
DO - 10.1016/j.psychres.2010.09.014
M3 - Article
C2 - 21055832
AN - SCOPUS:79952359698
VL - 186
SP - 356
EP - 361
JO - Psychiatry Research
JF - Psychiatry Research
SN - 0165-1781
IS - 2-3
ER -