Pseudomembranous colitis without diarrhea presenting clinically as acute intestinal pseudo-obstruction

Rafiq A. Sheikh, Shagufta Yasmeen, Mary Pat Pauly, Walter L. Trudeau

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Pseudomembranous colitis usually presents with diarrhea in a clinical setting of recent antibiotic use. It is uncommon to see it as a cause of obstipation and colonic pseudo-obstruction. We report an unusual case of an elderly woman with hypertension, congestive heart failure, chronic obstructive pulmonary disease, chronic renal insufficiency, and diabetes mellitus, who was admitted with fever, abdominal pain, and distension without diarrhea. She presented with decreased stool frequency and obstipation. She did not respond to conservative management. Colonoscopy revealed a picture of pseudomembranous colitis, and Clostridium difficile toxin was positive. She responded well to metronidazole therapy.

Original languageEnglish (US)
Pages (from-to)629-632
Number of pages4
JournalJournal of Gastroenterology
Issue number9
StatePublished - 2001


  • Clostridium difficile
  • Colitis
  • Pseudo-obstruction
  • Pseudomembranous

ASJC Scopus subject areas

  • Gastroenterology


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