Abstract
Platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are orthobiologic therapies considered as an alternative to the current therapies for muscle, bone and cartilage. Different formulations of biomaterials have been used as carriers for PRP and BMAC in order to increase regenerative processes. The most common biomaterials utilized in conjunction with PRP and BMAC clinical trials are organic scaffolds and natural or synthetic polymers. This review will cover the combinatorial strategies of biomaterial carriers with PRP and BMAC for musculoskeletal conditions (MsCs) repair and regeneration in clinical trials. The main objective is to review the therapeutic use of PRP and BMAC as a treatment option for muscle, bone and cartilage injuries.
| Original language | English (US) |
|---|---|
| Article number | 5328 |
| Journal | International journal of molecular sciences |
| Volume | 20 |
| Issue number | 21 |
| DOIs | |
| State | Published - Nov 1 2019 |
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Keywords
- Biomaterials
- Bone
- Bone marrow aspirate concentrate (BMAC)
- Cartilage
- Muscle
- Platelet Rich Plasma (PRP)
ASJC Scopus subject areas
- Catalysis
- Molecular Biology
- Spectroscopy
- Computer Science Applications
- Physical and Theoretical Chemistry
- Organic Chemistry
- Inorganic Chemistry
Cite this
PRP and BMAC for musculoskeletal conditions via biomaterial carriers. / Yamaguchi, Fabio S.M.; Shams, Shahin; Silva, Eduardo A.; Stilhano, Roberta S.
In: International journal of molecular sciences, Vol. 20, No. 21, 5328, 01.11.2019.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - PRP and BMAC for musculoskeletal conditions via biomaterial carriers
AU - Yamaguchi, Fabio S.M.
AU - Shams, Shahin
AU - Silva, Eduardo A.
AU - Stilhano, Roberta S.
PY - 2019/11/1
Y1 - 2019/11/1
N2 - Platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are orthobiologic therapies considered as an alternative to the current therapies for muscle, bone and cartilage. Different formulations of biomaterials have been used as carriers for PRP and BMAC in order to increase regenerative processes. The most common biomaterials utilized in conjunction with PRP and BMAC clinical trials are organic scaffolds and natural or synthetic polymers. This review will cover the combinatorial strategies of biomaterial carriers with PRP and BMAC for musculoskeletal conditions (MsCs) repair and regeneration in clinical trials. The main objective is to review the therapeutic use of PRP and BMAC as a treatment option for muscle, bone and cartilage injuries.
AB - Platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are orthobiologic therapies considered as an alternative to the current therapies for muscle, bone and cartilage. Different formulations of biomaterials have been used as carriers for PRP and BMAC in order to increase regenerative processes. The most common biomaterials utilized in conjunction with PRP and BMAC clinical trials are organic scaffolds and natural or synthetic polymers. This review will cover the combinatorial strategies of biomaterial carriers with PRP and BMAC for musculoskeletal conditions (MsCs) repair and regeneration in clinical trials. The main objective is to review the therapeutic use of PRP and BMAC as a treatment option for muscle, bone and cartilage injuries.
KW - Biomaterials
KW - Bone
KW - Bone marrow aspirate concentrate (BMAC)
KW - Cartilage
KW - Muscle
KW - Platelet Rich Plasma (PRP)
UR - http://www.scopus.com/inward/record.url?scp=85074411682&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85074411682&partnerID=8YFLogxK
U2 - 10.3390/ijms20215328
DO - 10.3390/ijms20215328
M3 - Review article
C2 - 31717698
AN - SCOPUS:85074411682
VL - 20
JO - International Journal of Molecular Sciences
JF - International Journal of Molecular Sciences
SN - 1661-6596
IS - 21
M1 - 5328
ER -