PRP and BMAC for musculoskeletal conditions via biomaterial carriers

Fabio S.M. Yamaguchi; Shahin Shams; Eduardo A. Silva; Roberta S. Stilhano

doi:10.3390/ijms20215328

PRP and BMAC for musculoskeletal conditions via biomaterial carriers

Fabio S.M. Yamaguchi, Shahin Shams, Eduardo A. Silva, Roberta S. Stilhano

Biomedical Engineering

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

Platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are orthobiologic therapies considered as an alternative to the current therapies for muscle, bone and cartilage. Different formulations of biomaterials have been used as carriers for PRP and BMAC in order to increase regenerative processes. The most common biomaterials utilized in conjunction with PRP and BMAC clinical trials are organic scaffolds and natural or synthetic polymers. This review will cover the combinatorial strategies of biomaterial carriers with PRP and BMAC for musculoskeletal conditions (MsCs) repair and regeneration in clinical trials. The main objective is to review the therapeutic use of PRP and BMAC as a treatment option for muscle, bone and cartilage injuries.

Original language	English (US)
Article number	5328
Journal	International journal of molecular sciences
Volume	20
Issue number	21
DOIs	https://doi.org/10.3390/ijms20215328
State	Published - Nov 1 2019

Keywords

Biomaterials
Bone
Bone marrow aspirate concentrate (BMAC)
Cartilage
Muscle
Platelet Rich Plasma (PRP)

ASJC Scopus subject areas

Catalysis
Molecular Biology
Spectroscopy
Computer Science Applications
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry

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10.3390/ijms20215328

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title = "PRP and BMAC for musculoskeletal conditions via biomaterial carriers",

abstract = "Platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are orthobiologic therapies considered as an alternative to the current therapies for muscle, bone and cartilage. Different formulations of biomaterials have been used as carriers for PRP and BMAC in order to increase regenerative processes. The most common biomaterials utilized in conjunction with PRP and BMAC clinical trials are organic scaffolds and natural or synthetic polymers. This review will cover the combinatorial strategies of biomaterial carriers with PRP and BMAC for musculoskeletal conditions (MsCs) repair and regeneration in clinical trials. The main objective is to review the therapeutic use of PRP and BMAC as a treatment option for muscle, bone and cartilage injuries.",

keywords = "Biomaterials, Bone, Bone marrow aspirate concentrate (BMAC), Cartilage, Muscle, Platelet Rich Plasma (PRP)",

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AU - Yamaguchi, Fabio S.M.

AU - Shams, Shahin

AU - Silva, Eduardo A.

AU - Stilhano, Roberta S.

PY - 2019/11/1

Y1 - 2019/11/1

N2 - Platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are orthobiologic therapies considered as an alternative to the current therapies for muscle, bone and cartilage. Different formulations of biomaterials have been used as carriers for PRP and BMAC in order to increase regenerative processes. The most common biomaterials utilized in conjunction with PRP and BMAC clinical trials are organic scaffolds and natural or synthetic polymers. This review will cover the combinatorial strategies of biomaterial carriers with PRP and BMAC for musculoskeletal conditions (MsCs) repair and regeneration in clinical trials. The main objective is to review the therapeutic use of PRP and BMAC as a treatment option for muscle, bone and cartilage injuries.

AB - Platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are orthobiologic therapies considered as an alternative to the current therapies for muscle, bone and cartilage. Different formulations of biomaterials have been used as carriers for PRP and BMAC in order to increase regenerative processes. The most common biomaterials utilized in conjunction with PRP and BMAC clinical trials are organic scaffolds and natural or synthetic polymers. This review will cover the combinatorial strategies of biomaterial carriers with PRP and BMAC for musculoskeletal conditions (MsCs) repair and regeneration in clinical trials. The main objective is to review the therapeutic use of PRP and BMAC as a treatment option for muscle, bone and cartilage injuries.

KW - Biomaterials

KW - Bone

KW - Bone marrow aspirate concentrate (BMAC)

KW - Cartilage

KW - Muscle

KW - Platelet Rich Plasma (PRP)

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PRP and BMAC for musculoskeletal conditions via biomaterial carriers

Abstract

Keywords

ASJC Scopus subject areas

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