Abstract
Thermotherapy is a promising technique for the minimally invasive elimination of solid tumors. Here we report the fabrication of protein-coated iron oxide NPs (12 nm core) for use as thermal therapeutic agents. These albumin-passivated NPs are stable under physiological conditions, with rapid heating and cell killing capacity upon alternating magnetic field (AMF) exposure. The mode of action is specific: no measurable cytotoxicity was observed for the particle without AMF or for AMF exposure without the particle.
Original language | English (US) |
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Pages (from-to) | 1204-1208 |
Number of pages | 5 |
Journal | Journal of Materials Chemistry |
Volume | 18 |
Issue number | 11 |
DOIs | |
State | Published - 2008 |
Externally published | Yes |
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Materials Chemistry
- Materials Science(all)