Prospects for minocycline neuroprotection

Jennifer M. Plane, Yan Shen, David E Pleasure, Wenbin Deng

Research output: Contribution to journalArticlepeer-review

200 Scopus citations

Abstract

Minocycline is a clinically available antibiotic and anti-inflammatory drug that also demonstrates neuroprotective properties in a variety of experimental models of neurological diseases. There have thus far been more than 300 publications on minocycline neuroprotection, including a growing number of human studies. Our objective is to critically review the biological basis and translational potential of this action of minocycline on the nervous system.

Original languageEnglish (US)
Pages (from-to)1442-1448
Number of pages7
JournalArchives of Neurology
Volume67
Issue number12
DOIs
StatePublished - Dec 2010

ASJC Scopus subject areas

  • Clinical Neurology

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