PROSPECTIVE STUDY OF CHLAMYDIAL INFECTION IN NEONATES

J. Schachter, J. Holt, E. Goodner, M. Grossman, Richard L Sweet, J. Mills

Research output: Contribution to journalArticle

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Abstract

Chlamydia trachomatis was recovered from the cervices of 4% (36/900) of pregnant women tested. 20 infants born through chlamydia-infected cervices were followed up for a year, as were 18 infants born to chlamydia-negative mothers. A statistically significant excess of conjunctivitis and pneumonia was found in infants exposed to chlamydia. The attack-rate for inclusion conjunctivitis was 35% (7/20) and for chlamydial pneumonia it was 20% (4/20). Chlamydiæ were recovered from 10 of the 20 (50%) exposed infants, and seroconversion was demonstrated in 14 (70%). None of the 18 unexposed infants showed evidence of chlamydial infection. Thus in our clinic 2·8% of all newborns acquired chlamydial infection, with incidence-rates of 14 cases of conjunctivitis and 8 cases of pneumonia per 1000 live births. Neonatal chlamydial infection is thus a major public-health problem warranting a preventive programme based on the fuller provision of diagnostic services and the treatment of infected pregnant women.

Original languageEnglish (US)
Pages (from-to)377-380
Number of pages4
JournalThe Lancet
Volume314
Issue number8139
DOIs
StatePublished - Aug 25 1979

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Newborn Infant
Prospective Studies
Chlamydia
Infection
Conjunctivitis
Cervix Uteri
Chlamydial Pneumonia
Pregnant Women
Pneumonia
Inclusion Conjunctivitis
Preventive Health Services
Diagnostic Services
Chlamydia trachomatis
Live Birth
Public Health
Mothers
Incidence
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Schachter, J., Holt, J., Goodner, E., Grossman, M., Sweet, R. L., & Mills, J. (1979). PROSPECTIVE STUDY OF CHLAMYDIAL INFECTION IN NEONATES. The Lancet, 314(8139), 377-380. https://doi.org/10.1016/S0140-6736(79)90400-8

PROSPECTIVE STUDY OF CHLAMYDIAL INFECTION IN NEONATES. / Schachter, J.; Holt, J.; Goodner, E.; Grossman, M.; Sweet, Richard L; Mills, J.

In: The Lancet, Vol. 314, No. 8139, 25.08.1979, p. 377-380.

Research output: Contribution to journalArticle

Schachter, J, Holt, J, Goodner, E, Grossman, M, Sweet, RL & Mills, J 1979, 'PROSPECTIVE STUDY OF CHLAMYDIAL INFECTION IN NEONATES', The Lancet, vol. 314, no. 8139, pp. 377-380. https://doi.org/10.1016/S0140-6736(79)90400-8
Schachter J, Holt J, Goodner E, Grossman M, Sweet RL, Mills J. PROSPECTIVE STUDY OF CHLAMYDIAL INFECTION IN NEONATES. The Lancet. 1979 Aug 25;314(8139):377-380. https://doi.org/10.1016/S0140-6736(79)90400-8
Schachter, J. ; Holt, J. ; Goodner, E. ; Grossman, M. ; Sweet, Richard L ; Mills, J. / PROSPECTIVE STUDY OF CHLAMYDIAL INFECTION IN NEONATES. In: The Lancet. 1979 ; Vol. 314, No. 8139. pp. 377-380.
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