Abstract
Chlamydia trachomatis was recovered from the cervices of 4% (36/900) of pregnant women tested. 20 infants born through chlamydia-infected cervices were followed up for a year, as were 18 infants born to chlamydia-negative mothers. A statistically significant excess of conjunctivitis and pneumonia was found in infants exposed to chlamydia. The attack-rate for inclusion conjunctivitis was 35% (7/20) and for chlamydial pneumonia it was 20% (4/20). Chlamydiæ were recovered from 10 of the 20 (50%) exposed infants, and seroconversion was demonstrated in 14 (70%). None of the 18 unexposed infants showed evidence of chlamydial infection. Thus in our clinic 2·8% of all newborns acquired chlamydial infection, with incidence-rates of 14 cases of conjunctivitis and 8 cases of pneumonia per 1000 live births. Neonatal chlamydial infection is thus a major public-health problem warranting a preventive programme based on the fuller provision of diagnostic services and the treatment of infected pregnant women.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 377-380 |
| Number of pages | 4 |
| Journal | The Lancet |
| Volume | 314 |
| Issue number | 8139 |
| DOIs | |
| State | Published - Aug 25 1979 |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
PROSPECTIVE STUDY OF CHLAMYDIAL INFECTION IN NEONATES. / Schachter, J.; Holt, J.; Goodner, E.; Grossman, M.; Sweet, Richard L; Mills, J.
In: The Lancet, Vol. 314, No. 8139, 25.08.1979, p. 377-380.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - PROSPECTIVE STUDY OF CHLAMYDIAL INFECTION IN NEONATES
AU - Schachter, J.
AU - Holt, J.
AU - Goodner, E.
AU - Grossman, M.
AU - Sweet, Richard L
AU - Mills, J.
PY - 1979/8/25
Y1 - 1979/8/25
N2 - Chlamydia trachomatis was recovered from the cervices of 4% (36/900) of pregnant women tested. 20 infants born through chlamydia-infected cervices were followed up for a year, as were 18 infants born to chlamydia-negative mothers. A statistically significant excess of conjunctivitis and pneumonia was found in infants exposed to chlamydia. The attack-rate for inclusion conjunctivitis was 35% (7/20) and for chlamydial pneumonia it was 20% (4/20). Chlamydiæ were recovered from 10 of the 20 (50%) exposed infants, and seroconversion was demonstrated in 14 (70%). None of the 18 unexposed infants showed evidence of chlamydial infection. Thus in our clinic 2·8% of all newborns acquired chlamydial infection, with incidence-rates of 14 cases of conjunctivitis and 8 cases of pneumonia per 1000 live births. Neonatal chlamydial infection is thus a major public-health problem warranting a preventive programme based on the fuller provision of diagnostic services and the treatment of infected pregnant women.
AB - Chlamydia trachomatis was recovered from the cervices of 4% (36/900) of pregnant women tested. 20 infants born through chlamydia-infected cervices were followed up for a year, as were 18 infants born to chlamydia-negative mothers. A statistically significant excess of conjunctivitis and pneumonia was found in infants exposed to chlamydia. The attack-rate for inclusion conjunctivitis was 35% (7/20) and for chlamydial pneumonia it was 20% (4/20). Chlamydiæ were recovered from 10 of the 20 (50%) exposed infants, and seroconversion was demonstrated in 14 (70%). None of the 18 unexposed infants showed evidence of chlamydial infection. Thus in our clinic 2·8% of all newborns acquired chlamydial infection, with incidence-rates of 14 cases of conjunctivitis and 8 cases of pneumonia per 1000 live births. Neonatal chlamydial infection is thus a major public-health problem warranting a preventive programme based on the fuller provision of diagnostic services and the treatment of infected pregnant women.
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U2 - 10.1016/S0140-6736(79)90400-8
DO - 10.1016/S0140-6736(79)90400-8
M3 - Article
C2 - 89446
AN - SCOPUS:0018645543
VL - 314
SP - 377
EP - 380
JO - The Lancet
JF - The Lancet
SN - 0140-6736
IS - 8139
ER -