PROSPECTIVE STUDY OF CHLAMYDIAL INFECTION IN NEONATES

J. Schachter, J. Holt, E. Goodner, M. Grossman, Richard L Sweet, J. Mills

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85 Scopus citations

Abstract

Chlamydia trachomatis was recovered from the cervices of 4% (36/900) of pregnant women tested. 20 infants born through chlamydia-infected cervices were followed up for a year, as were 18 infants born to chlamydia-negative mothers. A statistically significant excess of conjunctivitis and pneumonia was found in infants exposed to chlamydia. The attack-rate for inclusion conjunctivitis was 35% (7/20) and for chlamydial pneumonia it was 20% (4/20). Chlamydiæ were recovered from 10 of the 20 (50%) exposed infants, and seroconversion was demonstrated in 14 (70%). None of the 18 unexposed infants showed evidence of chlamydial infection. Thus in our clinic 2·8% of all newborns acquired chlamydial infection, with incidence-rates of 14 cases of conjunctivitis and 8 cases of pneumonia per 1000 live births. Neonatal chlamydial infection is thus a major public-health problem warranting a preventive programme based on the fuller provision of diagnostic services and the treatment of infected pregnant women.

Original languageEnglish (US)
Pages (from-to)377-380
Number of pages4
JournalThe Lancet
Volume314
Issue number8139
DOIs
StatePublished - Aug 25 1979

ASJC Scopus subject areas

  • Medicine(all)

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    Schachter, J., Holt, J., Goodner, E., Grossman, M., Sweet, R. L., & Mills, J. (1979). PROSPECTIVE STUDY OF CHLAMYDIAL INFECTION IN NEONATES. The Lancet, 314(8139), 377-380. https://doi.org/10.1016/S0140-6736(79)90400-8