Prophylactic antibiotics in hip and knee arthroplasty

John Meehan, Amir A. Jamali, Hien H Nguyen

Research output: Contribution to journalArticle

124 Citations (Scopus)

Abstract

▶ Prophylactic parenteral antibiotics have contributed to the present low rate of surgical site infections following hip and knee arthroplasty. ▶ Over the past decade, there has been a change in the pattern of methicillin-resistant Staphylococcus aureus infections from hospital-acquired to community-acquired. ▶ The findings of recent studies on screening programs to identify carriers of methicillin-resistant Staphylococcus aureus have been equivocal, with some studies showing that such programs reduce the rate of infections and others showing no effect on infection rates. ▶ Hospitals with antibiogramdata that reveal high Staphylococcus resistance should consider use of vancomycin as a prophylactic antibiotic.

Original languageEnglish (US)
Pages (from-to)2480-2489
Number of pages10
JournalJournal of Bone and Joint Surgery - Series A
Volume91
Issue number10
DOIs
StatePublished - Oct 1 2009

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Knee Replacement Arthroplasties
Methicillin-Resistant Staphylococcus aureus
Hip
Anti-Bacterial Agents
Surgical Wound Infection
Vancomycin
Cross Infection
Infection
Staphylococcus

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

Cite this

Prophylactic antibiotics in hip and knee arthroplasty. / Meehan, John; Jamali, Amir A.; Nguyen, Hien H.

In: Journal of Bone and Joint Surgery - Series A, Vol. 91, No. 10, 01.10.2009, p. 2480-2489.

Research output: Contribution to journalArticle

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