Prophylactic antibiotics in hip and knee arthroplasty

John Meehan, Amir A. Jamali, Hien H Nguyen

Research output: Contribution to journalArticlepeer-review

129 Scopus citations


▶ Prophylactic parenteral antibiotics have contributed to the present low rate of surgical site infections following hip and knee arthroplasty. ▶ Over the past decade, there has been a change in the pattern of methicillin-resistant Staphylococcus aureus infections from hospital-acquired to community-acquired. ▶ The findings of recent studies on screening programs to identify carriers of methicillin-resistant Staphylococcus aureus have been equivocal, with some studies showing that such programs reduce the rate of infections and others showing no effect on infection rates. ▶ Hospitals with antibiogramdata that reveal high Staphylococcus resistance should consider use of vancomycin as a prophylactic antibiotic.

Original languageEnglish (US)
Pages (from-to)2480-2489
Number of pages10
JournalJournal of Bone and Joint Surgery - Series A
Issue number10
StatePublished - Oct 1 2009

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine


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