Prophylactic amnioinfusion as a treatment for oligohydramnios in laboring patients: A prospective, randomized trial

David B Schrimmer, Charles J. Macri, Richard H. Paul

Research output: Contribution to journalArticle

53 Scopus citations


Prophylactic amnioinfusion was studied in a randomized sample of 305 patients with oligohydramnios in labor. One hundred seventy-five patients underwent amnioinfusion with the remainder serving as controls. Amniotic fluid was titrated to an amniotic fluid index >10.0 cm in the treatment group. Patients receiving amnioinfusion had significantly less operative intervention for fetal distress (p = 0.0001) and fewer cesarean sections (p = 0.0001). Umbilical artery pH at the time of delivery also was increased (p = 0.0001). Rates of amnionitis and endometritis were not significantly different between infused patients and controls, although the length of hospital stay was significantly decreased (p = 0.002) in the treatment group. Our data support earlier reports in the literature that amnioinfusion is a useful technique for decreasing intrapartum morbidity for both mother and fetus.

Original languageEnglish (US)
Pages (from-to)972-975
Number of pages4
JournalAmerican Journal of Obstetrics and Gynecology
Issue number4 PART 1
StatePublished - 1991
Externally publishedYes



  • Amnioinfusion
  • amniotic fluid index
  • fetal distress
  • operative intervention

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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