Prolymphocytic leukemia. Serial responses to therapy

J. F. Swift, H. G. Wold, David R Gandara, J. Redmond, C. B. George

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Prolymphocytic leukemia is a rare lymphoproliferative disorder characterized by marked lymphocytosis, massive splenomegaly, minimal lymphadenopathy, and poor prognosis. Previous reports have noted very short survival, and poor response to single agent alkylator chemotherapy. A small number of reports have shown response to combination chemotherapy regimens including Adriamycin (doxorubicin). A case of prolymphocytic leukemia with serial responses to combination chemotherapy and splenectomy resulting in significant prolongation of survival is reported.

Original languageEnglish (US)
Pages (from-to)978-980
Number of pages3
JournalCancer
Volume54
Issue number6
StatePublished - 1984
Externally publishedYes

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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    Swift, J. F., Wold, H. G., Gandara, D. R., Redmond, J., & George, C. B. (1984). Prolymphocytic leukemia. Serial responses to therapy. Cancer, 54(6), 978-980.