Prolymphocytic leukemia. Serial responses to therapy

J. F. Swift, H. G. Wold, David R Gandara, J. Redmond, C. B. George

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Prolymphocytic leukemia is a rare lymphoproliferative disorder characterized by marked lymphocytosis, massive splenomegaly, minimal lymphadenopathy, and poor prognosis. Previous reports have noted very short survival, and poor response to single agent alkylator chemotherapy. A small number of reports have shown response to combination chemotherapy regimens including Adriamycin (doxorubicin). A case of prolymphocytic leukemia with serial responses to combination chemotherapy and splenectomy resulting in significant prolongation of survival is reported.

Original languageEnglish (US)
Pages (from-to)978-980
Number of pages3
JournalCancer
Volume54
Issue number6
StatePublished - 1984
Externally publishedYes

Fingerprint

Prolymphocytic Leukemia
Combination Drug Therapy
Doxorubicin
Lymphocytosis
Lymphoproliferative Disorders
Alkylating Agents
Splenomegaly
Splenectomy
Drug Therapy
Therapeutics

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Swift, J. F., Wold, H. G., Gandara, D. R., Redmond, J., & George, C. B. (1984). Prolymphocytic leukemia. Serial responses to therapy. Cancer, 54(6), 978-980.

Prolymphocytic leukemia. Serial responses to therapy. / Swift, J. F.; Wold, H. G.; Gandara, David R; Redmond, J.; George, C. B.

In: Cancer, Vol. 54, No. 6, 1984, p. 978-980.

Research output: Contribution to journalArticle

Swift, JF, Wold, HG, Gandara, DR, Redmond, J & George, CB 1984, 'Prolymphocytic leukemia. Serial responses to therapy', Cancer, vol. 54, no. 6, pp. 978-980.
Swift JF, Wold HG, Gandara DR, Redmond J, George CB. Prolymphocytic leukemia. Serial responses to therapy. Cancer. 1984;54(6):978-980.
Swift, J. F. ; Wold, H. G. ; Gandara, David R ; Redmond, J. ; George, C. B. / Prolymphocytic leukemia. Serial responses to therapy. In: Cancer. 1984 ; Vol. 54, No. 6. pp. 978-980.
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