Abstract
We studied ten male distance runners before and after a marathon to determine the effects of prolonged exercise on serum lipoprotein values and the capacity to clear plasma triglycerides. Serum lipid and lipoprotein concentrations, intravenous fat clearance, and postheparin plasma lipolytic activities were measured 24 hours before and 18 hours after the race. The clearance rate of exogenous fat increased 76% ± 64%, postheparin lipoprotein lipase activity increased 46% ± 35%, and fasting triglyceride levels decreased 26% ± 13% after the race. High-density lipoprotein (HDL) cholesterol level increased 10% ± 8%, primarily due to a 19% ± 17% increase in the HDL2 subfraction. Changes in the clearance rate of exogenous fat were directly related to changes in HDL cholesterol level and the HDL2 subfraction. Thus the rise in HDL cholesterol concentrations after prolonged exercise may be a consequence of enhanced fat clearance.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2552-2555 |
| Number of pages | 4 |
| Journal | Journal of the American Medical Association |
| Volume | 256 |
| Issue number | 18 |
| DOIs | |
| State | Published - 1986 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
Prolonged exercise augments plasma triglyceride clearance. / Sady, S. P.; Thompson, P. D.; Cullinane, E. M.; Kantor, M. A.; Domagala, E.; Herbert, P. N.
In: Journal of the American Medical Association, Vol. 256, No. 18, 1986, p. 2552-2555.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prolonged exercise augments plasma triglyceride clearance
AU - Sady, S. P.
AU - Thompson, P. D.
AU - Cullinane, E. M.
AU - Kantor, M. A.
AU - Domagala, E.
AU - Herbert, P. N.
PY - 1986
Y1 - 1986
N2 - We studied ten male distance runners before and after a marathon to determine the effects of prolonged exercise on serum lipoprotein values and the capacity to clear plasma triglycerides. Serum lipid and lipoprotein concentrations, intravenous fat clearance, and postheparin plasma lipolytic activities were measured 24 hours before and 18 hours after the race. The clearance rate of exogenous fat increased 76% ± 64%, postheparin lipoprotein lipase activity increased 46% ± 35%, and fasting triglyceride levels decreased 26% ± 13% after the race. High-density lipoprotein (HDL) cholesterol level increased 10% ± 8%, primarily due to a 19% ± 17% increase in the HDL2 subfraction. Changes in the clearance rate of exogenous fat were directly related to changes in HDL cholesterol level and the HDL2 subfraction. Thus the rise in HDL cholesterol concentrations after prolonged exercise may be a consequence of enhanced fat clearance.
AB - We studied ten male distance runners before and after a marathon to determine the effects of prolonged exercise on serum lipoprotein values and the capacity to clear plasma triglycerides. Serum lipid and lipoprotein concentrations, intravenous fat clearance, and postheparin plasma lipolytic activities were measured 24 hours before and 18 hours after the race. The clearance rate of exogenous fat increased 76% ± 64%, postheparin lipoprotein lipase activity increased 46% ± 35%, and fasting triglyceride levels decreased 26% ± 13% after the race. High-density lipoprotein (HDL) cholesterol level increased 10% ± 8%, primarily due to a 19% ± 17% increase in the HDL2 subfraction. Changes in the clearance rate of exogenous fat were directly related to changes in HDL cholesterol level and the HDL2 subfraction. Thus the rise in HDL cholesterol concentrations after prolonged exercise may be a consequence of enhanced fat clearance.
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UR - http://www.scopus.com/inward/citedby.url?scp=0022896868&partnerID=8YFLogxK
U2 - 10.1001/jama.256.18.2552
DO - 10.1001/jama.256.18.2552
M3 - Article
C2 - 3773156
VL - 256
SP - 2552
EP - 2555
JO - JAMA - Journal of the American Medical Association
JF - JAMA - Journal of the American Medical Association
SN - 0002-9955
IS - 18
ER -