Prolonged exercise augments plasma triglyceride clearance

S. P. Sady, P. D. Thompson, E. M. Cullinane, M. A. Kantor, E. Domagala, P. N. Herbert

Research output: Contribution to journalArticle

Abstract

We studied ten male distance runners before and after a marathon to determine the effects of prolonged exercise on serum lipoprotein values and the capacity to clear plasma triglycerides. Serum lipid and lipoprotein concentrations, intravenous fat clearance, and postheparin plasma lipolytic activities were measured 24 hours before and 18 hours after the race. The clearance rate of exogenous fat increased 76% ± 64%, postheparin lipoprotein lipase activity increased 46% ± 35%, and fasting triglyceride levels decreased 26% ± 13% after the race. High-density lipoprotein (HDL) cholesterol level increased 10% ± 8%, primarily due to a 19% ± 17% increase in the HDL2 subfraction. Changes in the clearance rate of exogenous fat were directly related to changes in HDL cholesterol level and the HDL2 subfraction. Thus the rise in HDL cholesterol concentrations after prolonged exercise may be a consequence of enhanced fat clearance.

Original languageEnglish (US)
Pages (from-to)2552-2555
Number of pages4
JournalJournal of the American Medical Association
Volume256
Issue number18
DOIs
StatePublished - 1986
Externally publishedYes

Fingerprint

Triglycerides
Fats
Exercise
HDL Cholesterol
Lipoproteins
Lipoprotein Lipase
Serum
Fasting
Lipids

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Sady, S. P., Thompson, P. D., Cullinane, E. M., Kantor, M. A., Domagala, E., & Herbert, P. N. (1986). Prolonged exercise augments plasma triglyceride clearance. Journal of the American Medical Association, 256(18), 2552-2555. https://doi.org/10.1001/jama.256.18.2552

Prolonged exercise augments plasma triglyceride clearance. / Sady, S. P.; Thompson, P. D.; Cullinane, E. M.; Kantor, M. A.; Domagala, E.; Herbert, P. N.

In: Journal of the American Medical Association, Vol. 256, No. 18, 1986, p. 2552-2555.

Research output: Contribution to journalArticle

Sady, SP, Thompson, PD, Cullinane, EM, Kantor, MA, Domagala, E & Herbert, PN 1986, 'Prolonged exercise augments plasma triglyceride clearance', Journal of the American Medical Association, vol. 256, no. 18, pp. 2552-2555. https://doi.org/10.1001/jama.256.18.2552
Sady SP, Thompson PD, Cullinane EM, Kantor MA, Domagala E, Herbert PN. Prolonged exercise augments plasma triglyceride clearance. Journal of the American Medical Association. 1986;256(18):2552-2555. https://doi.org/10.1001/jama.256.18.2552
Sady, S. P. ; Thompson, P. D. ; Cullinane, E. M. ; Kantor, M. A. ; Domagala, E. ; Herbert, P. N. / Prolonged exercise augments plasma triglyceride clearance. In: Journal of the American Medical Association. 1986 ; Vol. 256, No. 18. pp. 2552-2555.
@article{152a6331255c49e2b6ada8e5603a9846,
title = "Prolonged exercise augments plasma triglyceride clearance",
abstract = "We studied ten male distance runners before and after a marathon to determine the effects of prolonged exercise on serum lipoprotein values and the capacity to clear plasma triglycerides. Serum lipid and lipoprotein concentrations, intravenous fat clearance, and postheparin plasma lipolytic activities were measured 24 hours before and 18 hours after the race. The clearance rate of exogenous fat increased 76{\%} ± 64{\%}, postheparin lipoprotein lipase activity increased 46{\%} ± 35{\%}, and fasting triglyceride levels decreased 26{\%} ± 13{\%} after the race. High-density lipoprotein (HDL) cholesterol level increased 10{\%} ± 8{\%}, primarily due to a 19{\%} ± 17{\%} increase in the HDL2 subfraction. Changes in the clearance rate of exogenous fat were directly related to changes in HDL cholesterol level and the HDL2 subfraction. Thus the rise in HDL cholesterol concentrations after prolonged exercise may be a consequence of enhanced fat clearance.",
author = "Sady, {S. P.} and Thompson, {P. D.} and Cullinane, {E. M.} and Kantor, {M. A.} and E. Domagala and Herbert, {P. N.}",
year = "1986",
doi = "10.1001/jama.256.18.2552",
language = "English (US)",
volume = "256",
pages = "2552--2555",
journal = "JAMA - Journal of the American Medical Association",
issn = "0002-9955",
publisher = "American Medical Association",
number = "18",

}

TY - JOUR

T1 - Prolonged exercise augments plasma triglyceride clearance

AU - Sady, S. P.

AU - Thompson, P. D.

AU - Cullinane, E. M.

AU - Kantor, M. A.

AU - Domagala, E.

AU - Herbert, P. N.

PY - 1986

Y1 - 1986

N2 - We studied ten male distance runners before and after a marathon to determine the effects of prolonged exercise on serum lipoprotein values and the capacity to clear plasma triglycerides. Serum lipid and lipoprotein concentrations, intravenous fat clearance, and postheparin plasma lipolytic activities were measured 24 hours before and 18 hours after the race. The clearance rate of exogenous fat increased 76% ± 64%, postheparin lipoprotein lipase activity increased 46% ± 35%, and fasting triglyceride levels decreased 26% ± 13% after the race. High-density lipoprotein (HDL) cholesterol level increased 10% ± 8%, primarily due to a 19% ± 17% increase in the HDL2 subfraction. Changes in the clearance rate of exogenous fat were directly related to changes in HDL cholesterol level and the HDL2 subfraction. Thus the rise in HDL cholesterol concentrations after prolonged exercise may be a consequence of enhanced fat clearance.

AB - We studied ten male distance runners before and after a marathon to determine the effects of prolonged exercise on serum lipoprotein values and the capacity to clear plasma triglycerides. Serum lipid and lipoprotein concentrations, intravenous fat clearance, and postheparin plasma lipolytic activities were measured 24 hours before and 18 hours after the race. The clearance rate of exogenous fat increased 76% ± 64%, postheparin lipoprotein lipase activity increased 46% ± 35%, and fasting triglyceride levels decreased 26% ± 13% after the race. High-density lipoprotein (HDL) cholesterol level increased 10% ± 8%, primarily due to a 19% ± 17% increase in the HDL2 subfraction. Changes in the clearance rate of exogenous fat were directly related to changes in HDL cholesterol level and the HDL2 subfraction. Thus the rise in HDL cholesterol concentrations after prolonged exercise may be a consequence of enhanced fat clearance.

UR - http://www.scopus.com/inward/record.url?scp=0022896868&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022896868&partnerID=8YFLogxK

U2 - 10.1001/jama.256.18.2552

DO - 10.1001/jama.256.18.2552

M3 - Article

C2 - 3773156

VL - 256

SP - 2552

EP - 2555

JO - JAMA - Journal of the American Medical Association

JF - JAMA - Journal of the American Medical Association

SN - 0002-9955

IS - 18

ER -