Prolonged dependence of ischemic penumbra on induced hypertension

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Abstract

BACKGROUND: Pharmacological elevation of blood pressure in acute stroke due to large artery occlusion may enhance collateral blood flow and salvage penumbral tissue. The duration of viability of human penumbral tissue under such circumstances is unclear. OBJECTIVE: To describe a patient presenting with acute middle cerebral artery occlusion treated with induced hypertension who had prolonged survival of penumbral tissue with subsequent infarct extension after pressor agents were withdrawn. CONCLUSIONS: Enhanced collateral flow by elevation of blood pressure may result in prolonged survival of the ischemic penumbra which remains dependent on persistent use of pressor agents.

Original languageEnglish (US)
Pages (from-to)296-297
Number of pages2
JournalNeurologist
Volume15
Issue number5
DOIs
StatePublished - Sep 2009

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Keywords

  • Acute treatment
  • Induced hypertension
  • Penumbra
  • Stroke

ASJC Scopus subject areas

  • Clinical Neurology

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