Proliferative arteriopathy of the nasal philtrum in a Saint Bernard dog. Case report

Vascular remodeling due to medial smooth muscle cell proliferation is a stereotypical response to vascular damage, regardless of the cause. Here, a case of ulcerative dermatitis due to localised proliferative arteriopathy of the nasal philtrum of a male Saint Bernard dog is reported. The presence of vimentin and smooth muscle actin positive cells proliferating from the media into the subintima of medium and small sized arteries was observed. Clinical presentation, diagnosis, probable pathogenesis and outcome are discussed.