Prolactin secretion in Sheehan's syndrome. Responses to thyrotropin-releasing hormone and metoclopramide

I. Jialal; R. Desai; M. C. Rajput; C. Naidoo; M. A. Omar; S. M. Joubert

Prolactin secretion in Sheehan's syndrome. Responses to thyrotropin-releasing hormone and metoclopramide

I. Jialal, R. Desai, M. C. Rajput, C. Naidoo, M. A. Omar, S. M. Joubert

Research output: Contribution to journal › Article › peer-review

Abstract

The prolactin response to thyrotropin-releasing hormone (TRH) and metoclopramide was studied in 16 patients with Sheehan's syndrome and in 16 matched controls in the follicular phase. Metoclopramide resulted in a greater prolactin response than TRH did in the controls. However, both stimuli failed to evoke any appreciable prolactin response in the patients with Sheehan's syndrome. Since metoclopramide is generally free of side effects and far cheaper than TRH, we recommend the prolactin response to metoclopramide as the preferred screening test in the diagnosis of Sheehan's syndrome.

Original language	English (US)
Pages (from-to)	487-490
Number of pages	4
Journal	Journal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume	31
Issue number	6
State	Published - 1986
Externally published	Yes

ASJC Scopus subject areas

Obstetrics and Gynecology
Reproductive Medicine

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title = "Prolactin secretion in Sheehan's syndrome. Responses to thyrotropin-releasing hormone and metoclopramide",

abstract = "The prolactin response to thyrotropin-releasing hormone (TRH) and metoclopramide was studied in 16 patients with Sheehan's syndrome and in 16 matched controls in the follicular phase. Metoclopramide resulted in a greater prolactin response than TRH did in the controls. However, both stimuli failed to evoke any appreciable prolactin response in the patients with Sheehan's syndrome. Since metoclopramide is generally free of side effects and far cheaper than TRH, we recommend the prolactin response to metoclopramide as the preferred screening test in the diagnosis of Sheehan's syndrome.",

author = "I. Jialal and R. Desai and Rajput, {M. C.} and C. Naidoo and Omar, {M. A.} and Joubert, {S. M.}",

year = "1986",

language = "English (US)",

volume = "31",

pages = "487--490",

journal = "The Journal of reproductive medicine",

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publisher = "Donna Kessel",

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TY - JOUR

T1 - Prolactin secretion in Sheehan's syndrome. Responses to thyrotropin-releasing hormone and metoclopramide

AU - Jialal, I.

AU - Desai, R.

AU - Rajput, M. C.

AU - Naidoo, C.

AU - Omar, M. A.

AU - Joubert, S. M.

PY - 1986

Y1 - 1986

N2 - The prolactin response to thyrotropin-releasing hormone (TRH) and metoclopramide was studied in 16 patients with Sheehan's syndrome and in 16 matched controls in the follicular phase. Metoclopramide resulted in a greater prolactin response than TRH did in the controls. However, both stimuli failed to evoke any appreciable prolactin response in the patients with Sheehan's syndrome. Since metoclopramide is generally free of side effects and far cheaper than TRH, we recommend the prolactin response to metoclopramide as the preferred screening test in the diagnosis of Sheehan's syndrome.

AB - The prolactin response to thyrotropin-releasing hormone (TRH) and metoclopramide was studied in 16 patients with Sheehan's syndrome and in 16 matched controls in the follicular phase. Metoclopramide resulted in a greater prolactin response than TRH did in the controls. However, both stimuli failed to evoke any appreciable prolactin response in the patients with Sheehan's syndrome. Since metoclopramide is generally free of side effects and far cheaper than TRH, we recommend the prolactin response to metoclopramide as the preferred screening test in the diagnosis of Sheehan's syndrome.

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AN - SCOPUS:0022617614

VL - 31

SP - 487

EP - 490

JO - The Journal of reproductive medicine

JF - The Journal of reproductive medicine

SN - 0024-7758

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