Abstract
The prolactin response to thyrotropin-releasing hormone (TRH) and metoclopramide was studied in 16 patients with Sheehan's syndrome and in 16 matched controls in the follicular phase. Metoclopramide resulted in a greater prolactin response than TRH did in the controls. However, both stimuli failed to evoke any appreciable prolactin response in the patients with Sheehan's syndrome. Since metoclopramide is generally free of side effects and far cheaper than TRH, we recommend the prolactin response to metoclopramide as the preferred screening test in the diagnosis of Sheehan's syndrome.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 487-490 |
| Number of pages | 4 |
| Journal | Journal of Reproductive Medicine for the Obstetrician and Gynecologist |
| Volume | 31 |
| Issue number | 6 |
| State | Published - 1986 |
| Externally published | Yes |
ASJC Scopus subject areas
- Obstetrics and Gynecology
- Reproductive Medicine
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Jialal, I., Desai, R., Rajput, M. C., Naidoo, C., Omar, M. A., & Joubert, S. M. (1986). Prolactin secretion in Sheehan's syndrome. Responses to thyrotropin-releasing hormone and metoclopramide. Journal of Reproductive Medicine for the Obstetrician and Gynecologist, 31(6), 487-490.