Abstract
Objective. - To determine whether blue-on-yellow perimetry reveals progression of glaucomatous damage before it is evident with standard white- on-white perimetry. Design. - A Humphrey field analyzer (Humphrey Instruments, San Leandro, Calif) was modified to perform blue-on-yellow perimetry to isolate and measure the sensitivity of short wavelength- sensitive mechanisms. Participants were tested annually with standard white- on-white automated perimetry and blue-on-yellow automated perimetry for 5 years. Patients. - Sixteen patients with early glaucomatous visual field loss in one or both eyes and 62 age-matched normal control subjects. Results. - At baseline, 25 (78.1%) of the 32 eyes exhibited larger deficits with blue-on- yellow perimetry, five (15.6%) had equivalent loss with both tests, and two (6.3%) had larger deficits with standard white-on-white perimetry. Seven (21.9%) of the 32 eyes demonstrated evidence of progressive visual field loss with standard white-on-white perimetry in 5 years, while the other 25 eyes (78.1%) were relatively stable. Deficits with blue-on-yellow perimetry were twice as large as deficits with white-on-white perimetry in the stable group and were three to four times as large in the group with progressive field loss. Conclusions. - Blue-on-yellow perimetry is effective in predicting which patients with early glaucomatous visual field loss are most likely to have progressive loss. The rate of progressive loss is greater with blue-on- yellow perimetry than with standard white-on-white perimetry.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 651-656 |
| Number of pages | 6 |
| Journal | Archives of Ophthalmology |
| Volume | 111 |
| Issue number | 5 |
| State | Published - 1993 |
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ASJC Scopus subject areas
- Ophthalmology
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Progression of early glaucomatous visual field loss as detected by blue- on-yellow and standard white-on-white automated perimetry. / Johnson, C. A.; Adams, A. J.; Casson, E. J.; Brandt, James D.
In: Archives of Ophthalmology, Vol. 111, No. 5, 1993, p. 651-656.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Progression of early glaucomatous visual field loss as detected by blue- on-yellow and standard white-on-white automated perimetry
AU - Johnson, C. A.
AU - Adams, A. J.
AU - Casson, E. J.
AU - Brandt, James D
PY - 1993
Y1 - 1993
N2 - Objective. - To determine whether blue-on-yellow perimetry reveals progression of glaucomatous damage before it is evident with standard white- on-white perimetry. Design. - A Humphrey field analyzer (Humphrey Instruments, San Leandro, Calif) was modified to perform blue-on-yellow perimetry to isolate and measure the sensitivity of short wavelength- sensitive mechanisms. Participants were tested annually with standard white- on-white automated perimetry and blue-on-yellow automated perimetry for 5 years. Patients. - Sixteen patients with early glaucomatous visual field loss in one or both eyes and 62 age-matched normal control subjects. Results. - At baseline, 25 (78.1%) of the 32 eyes exhibited larger deficits with blue-on- yellow perimetry, five (15.6%) had equivalent loss with both tests, and two (6.3%) had larger deficits with standard white-on-white perimetry. Seven (21.9%) of the 32 eyes demonstrated evidence of progressive visual field loss with standard white-on-white perimetry in 5 years, while the other 25 eyes (78.1%) were relatively stable. Deficits with blue-on-yellow perimetry were twice as large as deficits with white-on-white perimetry in the stable group and were three to four times as large in the group with progressive field loss. Conclusions. - Blue-on-yellow perimetry is effective in predicting which patients with early glaucomatous visual field loss are most likely to have progressive loss. The rate of progressive loss is greater with blue-on- yellow perimetry than with standard white-on-white perimetry.
AB - Objective. - To determine whether blue-on-yellow perimetry reveals progression of glaucomatous damage before it is evident with standard white- on-white perimetry. Design. - A Humphrey field analyzer (Humphrey Instruments, San Leandro, Calif) was modified to perform blue-on-yellow perimetry to isolate and measure the sensitivity of short wavelength- sensitive mechanisms. Participants were tested annually with standard white- on-white automated perimetry and blue-on-yellow automated perimetry for 5 years. Patients. - Sixteen patients with early glaucomatous visual field loss in one or both eyes and 62 age-matched normal control subjects. Results. - At baseline, 25 (78.1%) of the 32 eyes exhibited larger deficits with blue-on- yellow perimetry, five (15.6%) had equivalent loss with both tests, and two (6.3%) had larger deficits with standard white-on-white perimetry. Seven (21.9%) of the 32 eyes demonstrated evidence of progressive visual field loss with standard white-on-white perimetry in 5 years, while the other 25 eyes (78.1%) were relatively stable. Deficits with blue-on-yellow perimetry were twice as large as deficits with white-on-white perimetry in the stable group and were three to four times as large in the group with progressive field loss. Conclusions. - Blue-on-yellow perimetry is effective in predicting which patients with early glaucomatous visual field loss are most likely to have progressive loss. The rate of progressive loss is greater with blue-on- yellow perimetry than with standard white-on-white perimetry.
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UR - http://www.scopus.com/inward/citedby.url?scp=0027161746&partnerID=8YFLogxK
M3 - Article
C2 - 8489448
AN - SCOPUS:0027161746
VL - 111
SP - 651
EP - 656
JO - JAMA Ophthalmology
JF - JAMA Ophthalmology
SN - 2168-6165
IS - 5
ER -