Progress on developing adaptive optics-optical coherence tomography for in vivo retinal imaging: Monitoring and correction of eye motion artifacts

Robert Zawadzki, Arlie G. Capps, Dae Yu Kim, Athanasios Panorgias, Scott B. Stevenson, Bernd Hamann, John S Werner

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Recent progress in retinal image acquisition techniques, including optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO), combined with improved performance of adaptive optics (AO) instrumentation, has resulted in improvement in the quality of in vivo images of cellular structures in the human retina. Here, we present a short review of progress on developing AO-OCT instruments. Despite significant progress in imaging speed and resolution, eye movements present during acquisition of a retinal image with OCT introduce motion artifacts into the image, complicating analysis and registration. This effect is especially pronounced in high-resolution datasets acquired with AO-OCT instruments. Several retinal tracking systems have been introduced to correct retinal motion during data acquisition. We present a method for correcting motion artifacts in AO-OCT volume data after acquisition using simultaneously captured adaptive optics-scanning laser ophthalmoscope (AO-SLO) images. We extract transverse eye motion data from theAO-SLO images, assign a motion adjustment vector to each AO-OCTA-scan, and re-sample from the scattered data back onto a regular grid. The corrected volume data improve the accuracy of quantitative analyses of microscopic structures.

Original languageEnglish (US)
Article number6683119
JournalIEEE Journal on Selected Topics in Quantum Electronics
Volume20
Issue number2
DOIs
StatePublished - Mar 1 2014

Keywords

  • Aberration compensation
  • Adaptive optics
  • Imaging system
  • Motion artifact correction
  • Ophthalmology
  • Optical coherence tomography
  • Scanning laser ophthalmoscopy

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electrical and Electronic Engineering

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