Progress on developing adaptive optics-optical coherence tomography for in vivo retinal imaging: Monitoring and correction of eye motion artifacts

Robert Zawadzki, Arlie G. Capps, Dae Yu Kim, Athanasios Panorgias, Scott B. Stevenson, Bernd Hamann, John S Werner

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Recent progress in retinal image acquisition techniques, including optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO), combined with improved performance of adaptive optics (AO) instrumentation, has resulted in improvement in the quality of in vivo images of cellular structures in the human retina. Here, we present a short review of progress on developing AO-OCT instruments. Despite significant progress in imaging speed and resolution, eye movements present during acquisition of a retinal image with OCT introduce motion artifacts into the image, complicating analysis and registration. This effect is especially pronounced in high-resolution datasets acquired with AO-OCT instruments. Several retinal tracking systems have been introduced to correct retinal motion during data acquisition. We present a method for correcting motion artifacts in AO-OCT volume data after acquisition using simultaneously captured adaptive optics-scanning laser ophthalmoscope (AO-SLO) images. We extract transverse eye motion data from theAO-SLO images, assign a motion adjustment vector to each AO-OCTA-scan, and re-sample from the scattered data back onto a regular grid. The corrected volume data improve the accuracy of quantitative analyses of microscopic structures.

Original languageEnglish (US)
Article number6683119
JournalIEEE Journal on Selected Topics in Quantum Electronics
Volume20
Issue number2
DOIs
StatePublished - Mar 1 2014

Fingerprint

Adaptive optics
Optical tomography
adaptive optics
artifacts
tomography
Imaging techniques
Monitoring
retinal images
Scanning
data acquisition
scanning
Lasers
acquisition
eye movements
lasers
Eye movements
retina
Image acquisition
Image registration
Optical resolving power

Keywords

  • Aberration compensation
  • Adaptive optics
  • Imaging system
  • Motion artifact correction
  • Ophthalmology
  • Optical coherence tomography
  • Scanning laser ophthalmoscopy

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electrical and Electronic Engineering

Cite this

Progress on developing adaptive optics-optical coherence tomography for in vivo retinal imaging : Monitoring and correction of eye motion artifacts. / Zawadzki, Robert; Capps, Arlie G.; Kim, Dae Yu; Panorgias, Athanasios; Stevenson, Scott B.; Hamann, Bernd; Werner, John S.

In: IEEE Journal on Selected Topics in Quantum Electronics, Vol. 20, No. 2, 6683119, 01.03.2014.

Research output: Contribution to journalArticle

@article{ed273ea6211945bfa8c25ced78450bb9,
title = "Progress on developing adaptive optics-optical coherence tomography for in vivo retinal imaging: Monitoring and correction of eye motion artifacts",
abstract = "Recent progress in retinal image acquisition techniques, including optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO), combined with improved performance of adaptive optics (AO) instrumentation, has resulted in improvement in the quality of in vivo images of cellular structures in the human retina. Here, we present a short review of progress on developing AO-OCT instruments. Despite significant progress in imaging speed and resolution, eye movements present during acquisition of a retinal image with OCT introduce motion artifacts into the image, complicating analysis and registration. This effect is especially pronounced in high-resolution datasets acquired with AO-OCT instruments. Several retinal tracking systems have been introduced to correct retinal motion during data acquisition. We present a method for correcting motion artifacts in AO-OCT volume data after acquisition using simultaneously captured adaptive optics-scanning laser ophthalmoscope (AO-SLO) images. We extract transverse eye motion data from theAO-SLO images, assign a motion adjustment vector to each AO-OCTA-scan, and re-sample from the scattered data back onto a regular grid. The corrected volume data improve the accuracy of quantitative analyses of microscopic structures.",
keywords = "Aberration compensation, Adaptive optics, Imaging system, Motion artifact correction, Ophthalmology, Optical coherence tomography, Scanning laser ophthalmoscopy",
author = "Robert Zawadzki and Capps, {Arlie G.} and Kim, {Dae Yu} and Athanasios Panorgias and Stevenson, {Scott B.} and Bernd Hamann and Werner, {John S}",
year = "2014",
month = "3",
day = "1",
doi = "10.1109/JSTQE.2013.2288302",
language = "English (US)",
volume = "20",
journal = "IEEE Journal of Selected Topics in Quantum Electronics",
issn = "1077-260X",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
number = "2",

}

TY - JOUR

T1 - Progress on developing adaptive optics-optical coherence tomography for in vivo retinal imaging

T2 - Monitoring and correction of eye motion artifacts

AU - Zawadzki, Robert

AU - Capps, Arlie G.

AU - Kim, Dae Yu

AU - Panorgias, Athanasios

AU - Stevenson, Scott B.

AU - Hamann, Bernd

AU - Werner, John S

PY - 2014/3/1

Y1 - 2014/3/1

N2 - Recent progress in retinal image acquisition techniques, including optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO), combined with improved performance of adaptive optics (AO) instrumentation, has resulted in improvement in the quality of in vivo images of cellular structures in the human retina. Here, we present a short review of progress on developing AO-OCT instruments. Despite significant progress in imaging speed and resolution, eye movements present during acquisition of a retinal image with OCT introduce motion artifacts into the image, complicating analysis and registration. This effect is especially pronounced in high-resolution datasets acquired with AO-OCT instruments. Several retinal tracking systems have been introduced to correct retinal motion during data acquisition. We present a method for correcting motion artifacts in AO-OCT volume data after acquisition using simultaneously captured adaptive optics-scanning laser ophthalmoscope (AO-SLO) images. We extract transverse eye motion data from theAO-SLO images, assign a motion adjustment vector to each AO-OCTA-scan, and re-sample from the scattered data back onto a regular grid. The corrected volume data improve the accuracy of quantitative analyses of microscopic structures.

AB - Recent progress in retinal image acquisition techniques, including optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO), combined with improved performance of adaptive optics (AO) instrumentation, has resulted in improvement in the quality of in vivo images of cellular structures in the human retina. Here, we present a short review of progress on developing AO-OCT instruments. Despite significant progress in imaging speed and resolution, eye movements present during acquisition of a retinal image with OCT introduce motion artifacts into the image, complicating analysis and registration. This effect is especially pronounced in high-resolution datasets acquired with AO-OCT instruments. Several retinal tracking systems have been introduced to correct retinal motion during data acquisition. We present a method for correcting motion artifacts in AO-OCT volume data after acquisition using simultaneously captured adaptive optics-scanning laser ophthalmoscope (AO-SLO) images. We extract transverse eye motion data from theAO-SLO images, assign a motion adjustment vector to each AO-OCTA-scan, and re-sample from the scattered data back onto a regular grid. The corrected volume data improve the accuracy of quantitative analyses of microscopic structures.

KW - Aberration compensation

KW - Adaptive optics

KW - Imaging system

KW - Motion artifact correction

KW - Ophthalmology

KW - Optical coherence tomography

KW - Scanning laser ophthalmoscopy

UR - http://www.scopus.com/inward/record.url?scp=84990876768&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84990876768&partnerID=8YFLogxK

U2 - 10.1109/JSTQE.2013.2288302

DO - 10.1109/JSTQE.2013.2288302

M3 - Article

AN - SCOPUS:84990876768

VL - 20

JO - IEEE Journal of Selected Topics in Quantum Electronics

JF - IEEE Journal of Selected Topics in Quantum Electronics

SN - 1077-260X

IS - 2

M1 - 6683119

ER -