@inproceedings{558ac672a5cd4cb8a1399b9bd90b3371,
title = "Progress in measurements and interpretation of light-evoked retinal function using OCT-based optoretinography (ORG)",
abstract = "The development of functional retinal imaging is of great interest to clinical and experimental ophthalmology, because it should provide more sensitive tools for ocular diseases diagnostic that would go beyond current gold standard of simple evaluation of the static retinal morphology. In this presentation we will review our recent progress in measurements and interpretation of OCT-based optoretinograms (ORG) i.e., the paradigm of using NIR OCT to measure in vivo bleaching-induced changes in retinal morphology (transient changes in volume of individual neurons, or thickness of retinal layers). Specifically, comparison between different instrumentations used to acquire ORGs and between results acquired using clinical (human) and experimental (animal) systems will be presented. Additionally, intensity-based and phase-based ORG extraction framework will be presented. Finally, we will discuss our findings in the context of current understanding of measured process, being a result osmotically driven water movements between the photoreceptors, and other retinal neurons and its surroundings.",
keywords = "Functional retinal imaging, Light evoked optical signals, Optical Coherence Tomography, Optophysilogy, Optoretinography, Water transport, Homeostasis",
author = "Zawadzki, {Robert J.} and Pengfei Zhang and Ewelina Pijewska and Denise Valente and Meleppat, {Ratheesh K.} and Vienola, {Kari V.} and Karlen, {Sarah J.} and M. Szkulmowski and Werner, {John S.} and Pugh, {Edward N.} and Jonnal, {Ravi S.}",
note = "Funding Information: We thank UC Davis EyePod as well VSRI UC Davis Laboratory members, for help and support. This research was partially supported by NIH grants EY026556; EY031098 (RJZ), EY02660 (ENP), EY012576 (NEI Core Grant) and TEAM TECH program of the Foundation for Polish Science co-financed by the European Union under the European Regional Development Fund (POIR.04.04.00-00-2070/16-00) (MS) Publisher Copyright: {\textcopyright} 2021 The Author (s).; 2021 European Conferences on Biomedical Optics, ECBO 2021 ; Conference date: 20-06-2021 Through 24-06-2021",
year = "2021",
language = "English (US)",
series = "Optics InfoBase Conference Papers",
publisher = "The Optical Society",
booktitle = "European Conferences on Biomedical Optics, ECBO 2021",
address = "United States",
}