Abstract
Probiotics, microorganisms that have a favorable influence on physiologic and pathological processes of the host by their effect on the intestinal flora, may play a role in improving human health. One of the putative effects is the modulation of immune function. Thus, the mucosal immune system and methods to assess its function are reviewed briefly. Probiotic modulation of humoral, cellular and nonspecific immunity is reviewed, with emphasis placed on immune response in disease models. There are very few reports of human intervention studies with probiotics. However, some of the possible future directions for research with respect to probiotics, immunity, and human health are discussed. Although the application of probiotics has demonstrated trends with respect to altered aspects of immune response, the underlying mechanisms by which that occurs are unclear.
| Original language | English (US) |
|---|---|
| Journal | Journal of Nutrition |
| Volume | 130 |
| Issue number | 2 SUPPL. |
| State | Published - 2000 |
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Keywords
- Functional foods
- Immune response
- Lactic acid bacteria
- Mucosal immunity
- Probiotics
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Food Science
Cite this
Probiotic immunomodulation in health and disease. / Erickson, Kent L; Hubbard, Neil.
In: Journal of Nutrition, Vol. 130, No. 2 SUPPL., 2000.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Probiotic immunomodulation in health and disease
AU - Erickson, Kent L
AU - Hubbard, Neil
PY - 2000
Y1 - 2000
N2 - Probiotics, microorganisms that have a favorable influence on physiologic and pathological processes of the host by their effect on the intestinal flora, may play a role in improving human health. One of the putative effects is the modulation of immune function. Thus, the mucosal immune system and methods to assess its function are reviewed briefly. Probiotic modulation of humoral, cellular and nonspecific immunity is reviewed, with emphasis placed on immune response in disease models. There are very few reports of human intervention studies with probiotics. However, some of the possible future directions for research with respect to probiotics, immunity, and human health are discussed. Although the application of probiotics has demonstrated trends with respect to altered aspects of immune response, the underlying mechanisms by which that occurs are unclear.
AB - Probiotics, microorganisms that have a favorable influence on physiologic and pathological processes of the host by their effect on the intestinal flora, may play a role in improving human health. One of the putative effects is the modulation of immune function. Thus, the mucosal immune system and methods to assess its function are reviewed briefly. Probiotic modulation of humoral, cellular and nonspecific immunity is reviewed, with emphasis placed on immune response in disease models. There are very few reports of human intervention studies with probiotics. However, some of the possible future directions for research with respect to probiotics, immunity, and human health are discussed. Although the application of probiotics has demonstrated trends with respect to altered aspects of immune response, the underlying mechanisms by which that occurs are unclear.
KW - Functional foods
KW - Immune response
KW - Lactic acid bacteria
KW - Mucosal immunity
KW - Probiotics
UR - http://www.scopus.com/inward/record.url?scp=0033979854&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033979854&partnerID=8YFLogxK
M3 - Article
VL - 130
JO - Journal of Nutrition
JF - Journal of Nutrition
SN - 0022-3166
IS - 2 SUPPL.
ER -