Proactive control as a double-edged sword in autism spectrum disorder

Jeremy Hogeveen, Marie K. Krug, Matthew V. Elliott, Cameron S Carter, Marjorie Solomon Friedman

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Proactive control refers to the active representation of contextual information to bias cognitive processing and facilitate goal-directed behavior. Despite research suggesting that proactive control may be impaired in autism spectrum disorder (ASD), the associations between proactive control and clinical symptoms of ASD remain underspecified. Here, we combined a children's version of the AX Continuous Performance Task (AX-CPT) with gold standard clinical assessments in children with ASD (N = 34) or typical development (TYP; N = 45). After controlling for full-scale IQ (FSIQ), measures of proactive control were similar between ASD and TYP. However, specifically within ASD we observed paradoxical relationships between proactive control and clinical symptoms. Increased reliance on proactive control was associated with reduced attention problems and increased restricted and repetitive behaviors in ASD. Therefore, proactive control appears to represent a double-edged sword in ASD: improved attentional control at the cost of heightened behavioral inflexibility. This represents a compelling and new characterization of the specific association between cognitive control processes isolated in computerized laboratory tasks and the multidimensional cognitive symptoms characteristic of ASD.

Original languageEnglish (US)
Pages (from-to)429-435
Number of pages7
JournalJournal of Abnormal Psychology
Volume127
Issue number4
DOIs
StatePublished - May 1 2018

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Neurobehavioral Manifestations
Autism Spectrum Disorder
Task Performance and Analysis
Research

Keywords

  • Attention
  • Autism spectrum disorder
  • Cognitive control
  • Proactive control
  • Restricted and repetitive behaviors

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

Cite this

Proactive control as a double-edged sword in autism spectrum disorder. / Hogeveen, Jeremy; Krug, Marie K.; Elliott, Matthew V.; Carter, Cameron S; Friedman, Marjorie Solomon.

In: Journal of Abnormal Psychology, Vol. 127, No. 4, 01.05.2018, p. 429-435.

Research output: Contribution to journalArticle

Hogeveen, Jeremy ; Krug, Marie K. ; Elliott, Matthew V. ; Carter, Cameron S ; Friedman, Marjorie Solomon. / Proactive control as a double-edged sword in autism spectrum disorder. In: Journal of Abnormal Psychology. 2018 ; Vol. 127, No. 4. pp. 429-435.
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