Primary position upbeat nystagmus. Another central vestibular nystagmus?

T. Nakada, M. P. Remler

Research output: Contribution to journalArticlepeer-review

46 Scopus citations


Recent studies of the vestibulo-ocular reflex have revealed a distinct pathway from the anterior semicircular canal to the contralateral oculomotor nucleus via the superior vestibular nucleus. Axons of this pathway ascend in the brachium conjunctivum, while axons of the other semicircular canal pathways ascend in the medial longitudinal fasciculus (MLF). We report two cases of primary position upbeat nystagmus where lesions of the brachium conjunctivum were suggested by computed tomography (CT) scans. One of these lesions was confirmed at autopsy. We concluded that primary position upbeat nystagmus, like downbeat nystagmus, is a type of central vestibular nystagmus resulting from an imbalanced of vertical vestibulo-ocular relfex activity.

Original languageEnglish (US)
Pages (from-to)185-189
Number of pages5
JournalJournal of Clinical Neuro-Ophthalmology
Issue number3
StatePublished - 1981

ASJC Scopus subject areas

  • Clinical Neurology
  • Ophthalmology


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