Primary Lateral Sclerosis

Yvonne D. Rollins; Bjorn E Oskarsson; Steven P. Ringel

doi:10.1002/9781444317008.ch53

Primary Lateral Sclerosis

Yvonne D. Rollins, Bjorn E Oskarsson, Steven P. Ringel

Neurology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Original language	English (US)
Title of host publication	International Neurology: A Clinical Approach
Publisher	Wiley-Blackwell
Pages	203-204
Number of pages	2
ISBN (Print)	9781405157384
DOIs	https://doi.org/10.1002/9781444317008.ch53
State	Published - May 18 2010

Keywords

Clinical syndrome of PLS - rare, accounting for 1-3% of patients with motor neuron disease
EMG, useful in distinguishing PLS from ALS - based on absence of diffuse chronic denervation
Etiology of motor neuron degeneration - remaining unknown
No curative treatment - available for PLS
PLS, a diagnosis of exclusion - other disorders, including ALS
Primary lateral sclerosis
Primary lateral sclerosis (PLS), primary upper motor neuron (UMN) disorder
Progressive lower extremity spasticity without significant loss of strength - classic initial symptom

ASJC Scopus subject areas

Neuroscience(all)

Access to Document

10.1002/9781444317008.ch53

Cite this

Rollins, Y. D., Oskarsson, B. E., & Ringel, S. P. (2010). Primary Lateral Sclerosis. In International Neurology: A Clinical Approach (pp. 203-204). Wiley-Blackwell. https://doi.org/10.1002/9781444317008.ch53

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AU - Ringel, Steven P.

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KW - No curative treatment - available for PLS

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