Primary hypoparathyroidism in the dog. Report of 15 cases and review of 13 previously reported cases.

D. S. Bruyette, Edward C Feldman

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

Fifteen dogs with primary hypoparathyroidism diagnosed at the University of California Veterinary Medical Teaching Hospital were compared with 13 previously reported cases. Age, sex, breed, and historical and physical findings were similar in both groups of dogs. Middle-aged females were affected primarily. A history of neurologic or neuromuscular disease was present in all 28 dogs, with 18 dogs having seizures. Posterior lenticular cataract formation secondary to hypocalcemia was suspected in six dogs. The most characteristic biochemical finding in all dogs was profound hypocalcemia (less than 6.5 mg/dl) and mild hyperphosphatemia. Serum magnesium concentrations were decreased in two dogs. Serum parathyroid hormone concentrations were consistent with the diagnosis of primary hypoparathyroidism in eight of nine dogs. Lymphocytic parathyroiditis was diagnosed in the 12 dogs from which tissue was submitted for histopathology. Successful management of the patient depended on frequent monitoring of the serum calcium concentration during initial and maintenance therapy.

Original languageEnglish (US)
Pages (from-to)7-14
Number of pages8
JournalJournal of veterinary internal medicine / American College of Veterinary Internal Medicine
Volume2
Issue number1
StatePublished - Jan 1988

Fingerprint

hypoparathyroidism
Hypoparathyroidism
Dogs
dogs
hypocalcemia
Hypocalcemia
Serum
middle-aged adults
Capsule Opacification
neuromuscular disorders
Hyperphosphatemia
Neuromuscular Diseases
nervous system diseases
parathyroid hormone
cataract
seizures
Nervous System Diseases
Parathyroid Hormone
Teaching Hospitals
histopathology

ASJC Scopus subject areas

  • veterinary(all)

Cite this

@article{f5ecbbb3f4e14b0bb3a1919180226af5,
title = "Primary hypoparathyroidism in the dog. Report of 15 cases and review of 13 previously reported cases.",
abstract = "Fifteen dogs with primary hypoparathyroidism diagnosed at the University of California Veterinary Medical Teaching Hospital were compared with 13 previously reported cases. Age, sex, breed, and historical and physical findings were similar in both groups of dogs. Middle-aged females were affected primarily. A history of neurologic or neuromuscular disease was present in all 28 dogs, with 18 dogs having seizures. Posterior lenticular cataract formation secondary to hypocalcemia was suspected in six dogs. The most characteristic biochemical finding in all dogs was profound hypocalcemia (less than 6.5 mg/dl) and mild hyperphosphatemia. Serum magnesium concentrations were decreased in two dogs. Serum parathyroid hormone concentrations were consistent with the diagnosis of primary hypoparathyroidism in eight of nine dogs. Lymphocytic parathyroiditis was diagnosed in the 12 dogs from which tissue was submitted for histopathology. Successful management of the patient depended on frequent monitoring of the serum calcium concentration during initial and maintenance therapy.",
author = "Bruyette, {D. S.} and Feldman, {Edward C}",
year = "1988",
month = "1",
language = "English (US)",
volume = "2",
pages = "7--14",
journal = "Journal of Veterinary Internal Medicine",
issn = "0891-6640",
publisher = "Wiley-Blackwell",
number = "1",

}

TY - JOUR

T1 - Primary hypoparathyroidism in the dog. Report of 15 cases and review of 13 previously reported cases.

AU - Bruyette, D. S.

AU - Feldman, Edward C

PY - 1988/1

Y1 - 1988/1

N2 - Fifteen dogs with primary hypoparathyroidism diagnosed at the University of California Veterinary Medical Teaching Hospital were compared with 13 previously reported cases. Age, sex, breed, and historical and physical findings were similar in both groups of dogs. Middle-aged females were affected primarily. A history of neurologic or neuromuscular disease was present in all 28 dogs, with 18 dogs having seizures. Posterior lenticular cataract formation secondary to hypocalcemia was suspected in six dogs. The most characteristic biochemical finding in all dogs was profound hypocalcemia (less than 6.5 mg/dl) and mild hyperphosphatemia. Serum magnesium concentrations were decreased in two dogs. Serum parathyroid hormone concentrations were consistent with the diagnosis of primary hypoparathyroidism in eight of nine dogs. Lymphocytic parathyroiditis was diagnosed in the 12 dogs from which tissue was submitted for histopathology. Successful management of the patient depended on frequent monitoring of the serum calcium concentration during initial and maintenance therapy.

AB - Fifteen dogs with primary hypoparathyroidism diagnosed at the University of California Veterinary Medical Teaching Hospital were compared with 13 previously reported cases. Age, sex, breed, and historical and physical findings were similar in both groups of dogs. Middle-aged females were affected primarily. A history of neurologic or neuromuscular disease was present in all 28 dogs, with 18 dogs having seizures. Posterior lenticular cataract formation secondary to hypocalcemia was suspected in six dogs. The most characteristic biochemical finding in all dogs was profound hypocalcemia (less than 6.5 mg/dl) and mild hyperphosphatemia. Serum magnesium concentrations were decreased in two dogs. Serum parathyroid hormone concentrations were consistent with the diagnosis of primary hypoparathyroidism in eight of nine dogs. Lymphocytic parathyroiditis was diagnosed in the 12 dogs from which tissue was submitted for histopathology. Successful management of the patient depended on frequent monitoring of the serum calcium concentration during initial and maintenance therapy.

UR - http://www.scopus.com/inward/record.url?scp=0023841657&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023841657&partnerID=8YFLogxK

M3 - Article

C2 - 3065494

AN - SCOPUS:0023841657

VL - 2

SP - 7

EP - 14

JO - Journal of Veterinary Internal Medicine

JF - Journal of Veterinary Internal Medicine

SN - 0891-6640

IS - 1

ER -