Prevention of folate deficiency by food fortification. VI. The antimegaloblastic effect of folic acid fortified maize meal

N. Colman, Ralph Green, K. Stevens, J. Metz

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The antimegaloblastic effect of cooked folic acid fortified maize meal was tested by feeding the meal to 5 lactating patients with folate deficient megaloblastic anaemia. The dose of folic acid in the meal before cooking varied from 100 to 500 μg daily. One patient who received 100 μg daily had a suboptimal haematological response. Meal containing 300 and 500 μg daily produced optimal haematological response in all 4 patients so treated, and there was no secondary reticulocyte response in the 2 patients subsequently given pharmacological doses of folic acid. It is concluded that the fortified meal after cooking is an effective antimegaloblastic agent.

Original languageEnglish (US)
Pages (from-to)1795-1978
Number of pages184
JournalSouth African Medical Journal
Volume48
Issue number42
StatePublished - 1974
Externally publishedYes

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Folic Acid
Zea mays
Meals
Food
Cooking
Megaloblastic Anemia
Reticulocytes
Pharmacology

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Prevention of folate deficiency by food fortification. VI. The antimegaloblastic effect of folic acid fortified maize meal. / Colman, N.; Green, Ralph; Stevens, K.; Metz, J.

In: South African Medical Journal, Vol. 48, No. 42, 1974, p. 1795-1978.

Research output: Contribution to journalArticle

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