The antimegaloblastic effect of cooked folic acid fortified maize meal was tested by feeding the meal to 5 lactating patients with folate deficient megaloblastic anaemia. The dose of folic acid in the meal before cooking varied from 100 to 500 μg daily. One patient who received 100 μg daily had a suboptimal haematological response. Meal containing 300 and 500 μg daily produced optimal haematological response in all 4 patients so treated, and there was no secondary reticulocyte response in the 2 patients subsequently given pharmacological doses of folic acid. It is concluded that the fortified meal after cooking is an effective antimegaloblastic agent.
|Original language||English (US)|
|Number of pages||184|
|Journal||South African Medical Journal|
|State||Published - 1974|
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