Prevalence of equine herpesvirus-1 infection among Thoroughbreds residing on a farm on which the virus was endemic

James A. Brown, Samantha Mapes, Barry A. Ball, Aaron D J Hodder, Irwin Liu, Nicola Pusterla

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21 Citations (Scopus)

Abstract

Objective - To determine the incidence of equine herpesvirus-1 (EHV-1) infection among Thoroughbreds residing on a farm on which the virus was known to be endemic. Design - Prospective cohort study. Animals - 10 nonpregnant mares, 8 stallions, 16 weanlings, 11 racehorses, and 30 pregnant mares and their foals born during the 2006 foaling season. Procedures - Blood and nasopharygeal swab samples were collected every 3 to 5 weeks for 9 months, and placenta and colostrum samples were collected at foaling. All samples were submitted for testing for EHV-1 DNA with a PCR assay. A type-specific EHV-1 ELISA was used to determine antibody titers in mares and foals at birth, 12 to 24 hours after birth, and every 3 to 5 weeks thereafter. Results - Results of the PCR assay were positive for only 4 of the 1,330 samples collected (590 blood samples, 590 nasopharyngeal swab samples, 30 placentas, and 30 colostrum samples), with EHV-1 DNA detected in nasal secretions from 3 horses (pregnant mare, stallion, and racehorse) and in the placenta from 1 mare. Seroconversion was detected in 3 of 27 foals during the first month of life. Conclusions and Clinical Relevance - Results suggested that there was a low prevalence of EHV-1 infection among this population of Thoroughbreds even though the virus was known to be endemic on the farm and that pregnant mares could become infected without aborting. Analysis of nasopharyngeal swab samples appeared to be more sensitive than analysis of blood samples for detection of EHV-1 DNA.

Original languageEnglish (US)
Pages (from-to)577-580
Number of pages4
JournalJournal of the American Veterinary Medical Association
Volume231
Issue number4
DOIs
StatePublished - Aug 15 2007

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Equid Herpesvirus 1
Equid herpesvirus 1
Herpesviridae Infections
Viruses
viruses
farms
mares
infection
Placenta
Colostrum
placenta
foals
sampling
foaling
DNA
racehorses
Parturition
stallions
colostrum
Polymerase Chain Reaction

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Prevalence of equine herpesvirus-1 infection among Thoroughbreds residing on a farm on which the virus was endemic. / Brown, James A.; Mapes, Samantha; Ball, Barry A.; Hodder, Aaron D J; Liu, Irwin; Pusterla, Nicola.

In: Journal of the American Veterinary Medical Association, Vol. 231, No. 4, 15.08.2007, p. 577-580.

Research output: Contribution to journalArticle

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