Prevalence of clinically important traumatic brain injuries in children with minor blunt head trauma and isolated severe injury mechanisms

Lise E. Nigrovic, Lois K. Lee, John Hoyle, Rachel M. Stanley, Marc H. Gorelick, Michelle Miskin, Shireen M. Atabaki, Peter S. Dayan, James F Holmes Jr, Nathan Kuppermann

Research output: Contribution to journalArticlepeer-review

65 Scopus citations


Objective: To determine the prevalence of clinically important traumatic brain injuries (TBIs) with severe injury mechanisms in children with minor blunt head trauma but with no other risk factors from the Pediatric Emergency Care Applied Research Network (PECARN) TBI prediction rules (defined as isolated severe injury mechanisms). Design: Secondary analysis of a large prospective observational cohort study. Setting: Twenty-five emergency departments participating in the PECARN. Patients: Children with minor blunt head trauma and Glasgow Coma Scale scores of at least 14. Intervention: Treating clinicians completed a structured data form that included injury mechanism (severity categories defined a priori). Main Outcome Measures: Clinically important TBIs were defined as intracranial injuries resulting in death, neurosurgical intervention, intubation for more than 24 hours, or hospital admission for at least 2 nights. We investigated the rate of clinically important TBIs in children with either severe injury mechanisms or isolated severe injury mechanisms. Results: Of the 42 412 patients enrolled in the overall study, 42 099 (99%) had injury mechanisms recorded, and their data were included for analysis. Of all study patients, 5869 (14%) had severe injury mechanisms, and 3302 (8%) had isolated severe injury mechanisms. Overall, 367 children had clinically important TBIs (0.9%; 95% CI, 0.8%-1.0%). Of the 1327 children younger than 2 years with isolated severe injury mechanisms, 4 (0.3%; 95% CI, 0.1%-0.8%) had clinically important TBIs, as did 12 of the 1975 children 2 years or older (0.6%; 95% CI, 0.3%-1.1%). Conclusion: Children with isolated severe injury mechanisms are at low risk of clinically important TBI, and many do not require emergent neuroimaging.

Original languageEnglish (US)
Pages (from-to)356-361
Number of pages6
JournalArchives of Pediatrics and Adolescent Medicine
Issue number4
StatePublished - Apr 2012

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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