Abstract
The rhesus macaque breeding colony of the Oswaldo Cruz Foundation (FIOCRUZ) was established in 1932 from a founding stock of 100 animals. This population has remained closed to new animal introductions for almost 70 years. A serologic survey was performed to determine the prevalence of antibodies to selected viruses as a first approach to identifying viral pathogens endemic in this population. Banked serum samples were tested for antibodies to simian immunodeficiency virus (SIV), simian T-lymphotropic virus (STLV), simian type D retrovirus (SRV), cercopithecine herpesvirus type-1 (B virus), rhesus cytomegalovirus (RhCMV), measles virus (MV), and hepatitis A virus (HAV). All samples were negative for antibodies against the simian retroviruses. The overall prevalence of antibodies was 95% for RhCMV, 45% for B virus, 35% for HAV, and 1% for MV. Prevalence was found to vary by age group. Am. J. Primatol.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 123-128 |
| Number of pages | 6 |
| Journal | American Journal of Primatology |
| Volume | 59 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 1 2003 |
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Keywords
- Health monitoring
- Nonhuman primates
- Serological survey
- Serology
- Viruses
ASJC Scopus subject areas
- Animal Science and Zoology
Cite this
Prevalence of antibodies to selected viruses in a long-term closed breeding colony of rhesus macaques (Macaca mulatta) in Brazil. / Andrade, Marcia Ribeiro; Yee, Joann; Barry, Peter A; Spinner, Abigail; Roberts, Jeffrey A; Cabello, Pedro H.; Leite, Jose Paulo; Lerche, Nicholas W.
In: American Journal of Primatology, Vol. 59, No. 3, 01.03.2003, p. 123-128.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prevalence of antibodies to selected viruses in a long-term closed breeding colony of rhesus macaques (Macaca mulatta) in Brazil
AU - Andrade, Marcia Ribeiro
AU - Yee, Joann
AU - Barry, Peter A
AU - Spinner, Abigail
AU - Roberts, Jeffrey A
AU - Cabello, Pedro H.
AU - Leite, Jose Paulo
AU - Lerche, Nicholas W.
PY - 2003/3/1
Y1 - 2003/3/1
N2 - The rhesus macaque breeding colony of the Oswaldo Cruz Foundation (FIOCRUZ) was established in 1932 from a founding stock of 100 animals. This population has remained closed to new animal introductions for almost 70 years. A serologic survey was performed to determine the prevalence of antibodies to selected viruses as a first approach to identifying viral pathogens endemic in this population. Banked serum samples were tested for antibodies to simian immunodeficiency virus (SIV), simian T-lymphotropic virus (STLV), simian type D retrovirus (SRV), cercopithecine herpesvirus type-1 (B virus), rhesus cytomegalovirus (RhCMV), measles virus (MV), and hepatitis A virus (HAV). All samples were negative for antibodies against the simian retroviruses. The overall prevalence of antibodies was 95% for RhCMV, 45% for B virus, 35% for HAV, and 1% for MV. Prevalence was found to vary by age group. Am. J. Primatol.
AB - The rhesus macaque breeding colony of the Oswaldo Cruz Foundation (FIOCRUZ) was established in 1932 from a founding stock of 100 animals. This population has remained closed to new animal introductions for almost 70 years. A serologic survey was performed to determine the prevalence of antibodies to selected viruses as a first approach to identifying viral pathogens endemic in this population. Banked serum samples were tested for antibodies to simian immunodeficiency virus (SIV), simian T-lymphotropic virus (STLV), simian type D retrovirus (SRV), cercopithecine herpesvirus type-1 (B virus), rhesus cytomegalovirus (RhCMV), measles virus (MV), and hepatitis A virus (HAV). All samples were negative for antibodies against the simian retroviruses. The overall prevalence of antibodies was 95% for RhCMV, 45% for B virus, 35% for HAV, and 1% for MV. Prevalence was found to vary by age group. Am. J. Primatol.
KW - Health monitoring
KW - Nonhuman primates
KW - Serological survey
KW - Serology
KW - Viruses
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UR - http://www.scopus.com/inward/citedby.url?scp=0242584930&partnerID=8YFLogxK
U2 - 10.1002/ajp.10069
DO - 10.1002/ajp.10069
M3 - Article
C2 - 12619046
AN - SCOPUS:0242584930
VL - 59
SP - 123
EP - 128
JO - American Journal of Primatology
JF - American Journal of Primatology
SN - 0275-2565
IS - 3
ER -