Prevalence of antibodies to selected viruses in a long-term closed breeding colony of rhesus macaques (Macaca mulatta) in Brazil

Marcia Ribeiro Andrade, Joann Yee, Peter A Barry, Abigail Spinner, Jeffrey A Roberts, Pedro H. Cabello, Jose Paulo Leite, Nicholas W. Lerche

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37 Scopus citations


The rhesus macaque breeding colony of the Oswaldo Cruz Foundation (FIOCRUZ) was established in 1932 from a founding stock of 100 animals. This population has remained closed to new animal introductions for almost 70 years. A serologic survey was performed to determine the prevalence of antibodies to selected viruses as a first approach to identifying viral pathogens endemic in this population. Banked serum samples were tested for antibodies to simian immunodeficiency virus (SIV), simian T-lymphotropic virus (STLV), simian type D retrovirus (SRV), cercopithecine herpesvirus type-1 (B virus), rhesus cytomegalovirus (RhCMV), measles virus (MV), and hepatitis A virus (HAV). All samples were negative for antibodies against the simian retroviruses. The overall prevalence of antibodies was 95% for RhCMV, 45% for B virus, 35% for HAV, and 1% for MV. Prevalence was found to vary by age group. Am. J. Primatol.

Original languageEnglish (US)
Pages (from-to)123-128
Number of pages6
JournalAmerican Journal of Primatology
Issue number3
StatePublished - Mar 1 2003



  • Health monitoring
  • Nonhuman primates
  • Serological survey
  • Serology
  • Viruses

ASJC Scopus subject areas

  • Animal Science and Zoology

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