Prevalence of antibodies to selected viruses in a long-term closed breeding colony of rhesus macaques (Macaca mulatta) in Brazil

Marcia Ribeiro Andrade; Joann Yee; Peter A Barry; Abigail Spinner; Jeffrey A Roberts; Pedro H. Cabello; Jose Paulo Leite; Nicholas W. Lerche

doi:10.1002/ajp.10069

Prevalence of antibodies to selected viruses in a long-term closed breeding colony of rhesus macaques (Macaca mulatta) in Brazil

Marcia Ribeiro Andrade, Joann Yee, Peter A Barry, Abigail Spinner, Jeffrey A Roberts, Pedro H. Cabello, Jose Paulo Leite, Nicholas W. Lerche

Research output: Contribution to journal › Article

38 Scopus citations

Abstract

The rhesus macaque breeding colony of the Oswaldo Cruz Foundation (FIOCRUZ) was established in 1932 from a founding stock of 100 animals. This population has remained closed to new animal introductions for almost 70 years. A serologic survey was performed to determine the prevalence of antibodies to selected viruses as a first approach to identifying viral pathogens endemic in this population. Banked serum samples were tested for antibodies to simian immunodeficiency virus (SIV), simian T-lymphotropic virus (STLV), simian type D retrovirus (SRV), cercopithecine herpesvirus type-1 (B virus), rhesus cytomegalovirus (RhCMV), measles virus (MV), and hepatitis A virus (HAV). All samples were negative for antibodies against the simian retroviruses. The overall prevalence of antibodies was 95% for RhCMV, 45% for B virus, 35% for HAV, and 1% for MV. Prevalence was found to vary by age group. Am. J. Primatol.

Original language	English (US)
Pages (from-to)	123-128
Number of pages	6
Journal	American Journal of Primatology
Volume	59
Issue number	3
DOIs	https://doi.org/10.1002/ajp.10069
State	Published - Mar 1 2003

Keywords

Health monitoring
Nonhuman primates
Serological survey
Serology
Viruses

ASJC Scopus subject areas

Animal Science and Zoology

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Andrade, M. R., Yee, J., Barry, P. A., Spinner, A., Roberts, J. A., Cabello, P. H., Leite, J. P., & Lerche, N. W. (2003). Prevalence of antibodies to selected viruses in a long-term closed breeding colony of rhesus macaques (Macaca mulatta) in Brazil. American Journal of Primatology, 59(3), 123-128. https://doi.org/10.1002/ajp.10069

Prevalence of antibodies to selected viruses in a long-term closed breeding colony of rhesus macaques (Macaca mulatta) in Brazil. / Andrade, Marcia Ribeiro; Yee, Joann; Barry, Peter A; Spinner, Abigail; Roberts, Jeffrey A; Cabello, Pedro H.; Leite, Jose Paulo; Lerche, Nicholas W.

In: American Journal of Primatology, Vol. 59, No. 3, 01.03.2003, p. 123-128.

Research output: Contribution to journal › Article

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