Abstract
Objective: This article reports on a prevalence study of dementia and Alzheimer's disease among two groups of subjects with the same ethnic background but widely differing environments. Method: The study was conducted among residents aged 65 years and older in two communities: Yorubas (N=2,494) living in Ibadan, Nigeria, and African Americans (N=2,212 in the community and N=106 in nursing homes) living in Indianapolis, Indiana. The study design consisted of a screening stage followed by a clinical assessment stage for selected subjects on the basis of their performance on the screening tests. Results: The age-adjusted prevalence rates of dementia (2.29%) and Alzheimer's disease (1.41%) in the Ibadan sample were significantly lower than those in the Indianapolis sample, both in the community-dwelling subjects alone [4.82%, and 3.69%, respectively) and in the combined nursing home and community samples (8.24% and 6.24%, respectively). The prevalence rates of dementia and Alzheimer's disease increased consistently with advancing age in both study groups. Conclusions: To the authors' knowledge, this is the first study, using the same research method at the two sites, to report significant differences in rates of dementia and Alzheimer's disease in two different communities with similar ethnic origins.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1485-1492 |
| Number of pages | 8 |
| Journal | American Journal of Psychiatry |
| Volume | 152 |
| Issue number | 10 |
| DOIs | |
| State | Published - Oct 1995 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Psychiatry and Mental health
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Prevalence of Alzheimer's disease and dementia in two communities : Nigerian Africans and African Americans. / Hendrie, Hugh C.; Osuntokun, Benjamin O.; Hall, Kathleen S.; Ogunniyi, Adesola O.; Hui, Siu L.; Unverzagt, Frederick W.; Gureje, Oyewusi; Rodenberg, Cynthia A.; Baiyewu, Olusegun; Musick, Beverly S.; Adeyinka, Abiodun; Farlow, Martin R.; Oluwole, S. O.; Class, C. Andrew; Komolafe, O.; Brashear, Allison; Burdine, Vicki.
In: American Journal of Psychiatry, Vol. 152, No. 10, 10.1995, p. 1485-1492.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prevalence of Alzheimer's disease and dementia in two communities
T2 - Nigerian Africans and African Americans
AU - Hendrie, Hugh C.
AU - Osuntokun, Benjamin O.
AU - Hall, Kathleen S.
AU - Ogunniyi, Adesola O.
AU - Hui, Siu L.
AU - Unverzagt, Frederick W.
AU - Gureje, Oyewusi
AU - Rodenberg, Cynthia A.
AU - Baiyewu, Olusegun
AU - Musick, Beverly S.
AU - Adeyinka, Abiodun
AU - Farlow, Martin R.
AU - Oluwole, S. O.
AU - Class, C. Andrew
AU - Komolafe, O.
AU - Brashear, Allison
AU - Burdine, Vicki
PY - 1995/10
Y1 - 1995/10
N2 - Objective: This article reports on a prevalence study of dementia and Alzheimer's disease among two groups of subjects with the same ethnic background but widely differing environments. Method: The study was conducted among residents aged 65 years and older in two communities: Yorubas (N=2,494) living in Ibadan, Nigeria, and African Americans (N=2,212 in the community and N=106 in nursing homes) living in Indianapolis, Indiana. The study design consisted of a screening stage followed by a clinical assessment stage for selected subjects on the basis of their performance on the screening tests. Results: The age-adjusted prevalence rates of dementia (2.29%) and Alzheimer's disease (1.41%) in the Ibadan sample were significantly lower than those in the Indianapolis sample, both in the community-dwelling subjects alone [4.82%, and 3.69%, respectively) and in the combined nursing home and community samples (8.24% and 6.24%, respectively). The prevalence rates of dementia and Alzheimer's disease increased consistently with advancing age in both study groups. Conclusions: To the authors' knowledge, this is the first study, using the same research method at the two sites, to report significant differences in rates of dementia and Alzheimer's disease in two different communities with similar ethnic origins.
AB - Objective: This article reports on a prevalence study of dementia and Alzheimer's disease among two groups of subjects with the same ethnic background but widely differing environments. Method: The study was conducted among residents aged 65 years and older in two communities: Yorubas (N=2,494) living in Ibadan, Nigeria, and African Americans (N=2,212 in the community and N=106 in nursing homes) living in Indianapolis, Indiana. The study design consisted of a screening stage followed by a clinical assessment stage for selected subjects on the basis of their performance on the screening tests. Results: The age-adjusted prevalence rates of dementia (2.29%) and Alzheimer's disease (1.41%) in the Ibadan sample were significantly lower than those in the Indianapolis sample, both in the community-dwelling subjects alone [4.82%, and 3.69%, respectively) and in the combined nursing home and community samples (8.24% and 6.24%, respectively). The prevalence rates of dementia and Alzheimer's disease increased consistently with advancing age in both study groups. Conclusions: To the authors' knowledge, this is the first study, using the same research method at the two sites, to report significant differences in rates of dementia and Alzheimer's disease in two different communities with similar ethnic origins.
UR - http://www.scopus.com/inward/record.url?scp=0029133072&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029133072&partnerID=8YFLogxK
U2 - 10.1176/ajp.152.10.1485
DO - 10.1176/ajp.152.10.1485
M3 - Article
C2 - 7573588
AN - SCOPUS:0029133072
VL - 152
SP - 1485
EP - 1492
JO - American Journal of Psychiatry
JF - American Journal of Psychiatry
SN - 0002-953X
IS - 10
ER -