TY - JOUR
T1 - Prevalence and correlates of physical and sexual abuse in children and adolescents with bipolar disorder
AU - Romero, Soledad
AU - Birmaher, Boris
AU - Axelson, David
AU - Goldstein, Tina
AU - Goldstein, Benjamin I.
AU - Gill, Mary Kay
AU - Iosif, Ana-Maria
AU - Strober, Michael A.
AU - Hunt, Jeffrey
AU - Esposito-Smythers, Christianne
AU - Ryan, Neal D.
AU - Leonard, Henrietta
AU - Keller, Martin
PY - 2009/1
Y1 - 2009/1
N2 - Objective: Adult bipolar disorder (BP) has been associated with lifetime history of physical and sexual abuse. However, there are no reports of the prevalence of abuse in BP youth. The objective of this study was to examine the prevalence and correlates of physical and/or sexual abuse among youth with BP spectrum disorders. Methods: Four hundred forty-six youths, ages 7 to 17 years (12.7 ± 3.2), meeting DSM-IV criteria for BP-I (n = 260), BP-II (n = 32) or operationalized definition of BP-NOS (n = 154) were assessed using the Schedule for Affective Disorders and Schizophrenia for School Age Children-Present and Lifetime version (K-SADS-PL). Abuse was ascertained using the K-SADS. Results: Twenty percent of the sample experienced physical and/or sexual abuse. The most robust correlates of any abuse history were living with a non-intact family (OR = 2.6), lifetime history of posttraumatic stress disorder (PTSD) (OR = 8.8), psychosis (OR = 2.1), conduct disorder (CD) (OR = 2.3), and first-degree family history of mood disorder (OR = 2.2). After adjusting for confounding demographic factors, physical abuse was associated with longer duration of BP illness, non-intact family, PTSD, psychosis, and first-degree family history of mood disorder. Sexual abuse was associated with PTSD. Subjects with both types of abuse were older, with longer illness duration, non-intact family, and greater prevalence of PTSD and CD as compared with the non-abused group. Limitations: Retrospective data. Also, since this is a cross-sectional study, no inferences regarding causality can be made. Conclusion: Sexual and/or physical abuse is common in youth with BP particularly in subjects with comorbid PTSD, psychosis, or CD. Prompt identification and treatment of these youth is warranted.
AB - Objective: Adult bipolar disorder (BP) has been associated with lifetime history of physical and sexual abuse. However, there are no reports of the prevalence of abuse in BP youth. The objective of this study was to examine the prevalence and correlates of physical and/or sexual abuse among youth with BP spectrum disorders. Methods: Four hundred forty-six youths, ages 7 to 17 years (12.7 ± 3.2), meeting DSM-IV criteria for BP-I (n = 260), BP-II (n = 32) or operationalized definition of BP-NOS (n = 154) were assessed using the Schedule for Affective Disorders and Schizophrenia for School Age Children-Present and Lifetime version (K-SADS-PL). Abuse was ascertained using the K-SADS. Results: Twenty percent of the sample experienced physical and/or sexual abuse. The most robust correlates of any abuse history were living with a non-intact family (OR = 2.6), lifetime history of posttraumatic stress disorder (PTSD) (OR = 8.8), psychosis (OR = 2.1), conduct disorder (CD) (OR = 2.3), and first-degree family history of mood disorder (OR = 2.2). After adjusting for confounding demographic factors, physical abuse was associated with longer duration of BP illness, non-intact family, PTSD, psychosis, and first-degree family history of mood disorder. Sexual abuse was associated with PTSD. Subjects with both types of abuse were older, with longer illness duration, non-intact family, and greater prevalence of PTSD and CD as compared with the non-abused group. Limitations: Retrospective data. Also, since this is a cross-sectional study, no inferences regarding causality can be made. Conclusion: Sexual and/or physical abuse is common in youth with BP particularly in subjects with comorbid PTSD, psychosis, or CD. Prompt identification and treatment of these youth is warranted.
KW - Bipolar disorder
KW - Children and adolescents
KW - Physical abuse
KW - Sexual abuse
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U2 - 10.1016/j.jad.2008.04.005
DO - 10.1016/j.jad.2008.04.005
M3 - Article
C2 - 18538857
AN - SCOPUS:56249111303
VL - 112
SP - 144
EP - 150
JO - Journal of Affective Disorders
JF - Journal of Affective Disorders
SN - 0165-0327
IS - 1-3
ER -