Presumed primary orbital neuroblastoma in a 20-month-old female

Nanfei Zhang, Lily Koo Lin

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Neuroblastoma is the most common malignant disease of childhood, and it often arises from either the adrenal gland or along the sympathetic chain. The authors report a case of a 20-month-old female with a presumed primary neuroblastoma of the orbit. Radiologically, the tumor showed a brightly enhancing mass lesion of the left side with intraorbital, temporal extraorbital, transsphenoid, and intracranial components. Histopathologically, the tumor was composed of small round blue cells. Immunohistochemical staining was positive for neuron-specific enolase. To the best of the authors knowledge, primary orbital neuroblastoma has only been previously reported once in children, although it has been reported twice in adults.

Original languageEnglish (US)
Pages (from-to)383-385
Number of pages3
JournalOphthalmic Plastic and Reconstructive Surgery
Issue number5
StatePublished - Sep 2010

ASJC Scopus subject areas

  • Ophthalmology
  • Surgery


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