Abstract
Delivery systems with sustained release of nisin have been proposed to improve stability and long-term effectiveness of this bacteriocin in foods. In this study, nisin was encapsulated in alginate (Alg) and alginate-resistant starch (Alg-RS) microparticles and its release was investigated. Studies found that the nisin concentration has significant influence on encapsulation efficiency (EE), loading capacity (LC) and size of both microparticles. Furthermore, encapsulation efficiency and loading capacity values were more increased by the addition of resistant starch to the alginate formulation. The highest encapsulation efficiency was obtained with Alg-RS microparticles prepared using initial nisin to alginate weight ratio of 25% w/w (59.77 ± 2.26%). Fourier transform-infrared (FT-IR) spectroscopy, X-ray diffraction (XRD) and differential scanning calorimetry (DSC) results confirmed the presence of nisin in the microparticles. The in vitro nisin release from these microparticles followed a controlled-release pattern consistent with a Fickian diffusion mechanism. The release rate from Alg-RS microparticles was less than that from the Alg microparticles.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 573-580 |
| Number of pages | 8 |
| Journal | Carbohydrate Polymers |
| Volume | 103 |
| Issue number | 1 |
| DOIs | |
| State | Published - Mar 15 2014 |
Fingerprint
Keywords
- Alginate
- Microparticle
- Nisin
- Resistant starch
ASJC Scopus subject areas
- Organic Chemistry
- Materials Chemistry
- Polymers and Plastics
Cite this
Preparation and characterization of alginate and alginate-resistant starch microparticles containing nisin. / Hosseini, Seyede Marzieh; Hosseini, Hedayat; Mohammadifar, Mohammad Amin; German, J. Bruce; Mortazavian, Amir Mohammad; Mohammadi, Abdorreza; Khosravi-Darani, Kianoosh; Shojaee-Aliabadi, Saeedeh; Khaksar, Ramin.
In: Carbohydrate Polymers, Vol. 103, No. 1, 15.03.2014, p. 573-580.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Preparation and characterization of alginate and alginate-resistant starch microparticles containing nisin
AU - Hosseini, Seyede Marzieh
AU - Hosseini, Hedayat
AU - Mohammadifar, Mohammad Amin
AU - German, J. Bruce
AU - Mortazavian, Amir Mohammad
AU - Mohammadi, Abdorreza
AU - Khosravi-Darani, Kianoosh
AU - Shojaee-Aliabadi, Saeedeh
AU - Khaksar, Ramin
PY - 2014/3/15
Y1 - 2014/3/15
N2 - Delivery systems with sustained release of nisin have been proposed to improve stability and long-term effectiveness of this bacteriocin in foods. In this study, nisin was encapsulated in alginate (Alg) and alginate-resistant starch (Alg-RS) microparticles and its release was investigated. Studies found that the nisin concentration has significant influence on encapsulation efficiency (EE), loading capacity (LC) and size of both microparticles. Furthermore, encapsulation efficiency and loading capacity values were more increased by the addition of resistant starch to the alginate formulation. The highest encapsulation efficiency was obtained with Alg-RS microparticles prepared using initial nisin to alginate weight ratio of 25% w/w (59.77 ± 2.26%). Fourier transform-infrared (FT-IR) spectroscopy, X-ray diffraction (XRD) and differential scanning calorimetry (DSC) results confirmed the presence of nisin in the microparticles. The in vitro nisin release from these microparticles followed a controlled-release pattern consistent with a Fickian diffusion mechanism. The release rate from Alg-RS microparticles was less than that from the Alg microparticles.
AB - Delivery systems with sustained release of nisin have been proposed to improve stability and long-term effectiveness of this bacteriocin in foods. In this study, nisin was encapsulated in alginate (Alg) and alginate-resistant starch (Alg-RS) microparticles and its release was investigated. Studies found that the nisin concentration has significant influence on encapsulation efficiency (EE), loading capacity (LC) and size of both microparticles. Furthermore, encapsulation efficiency and loading capacity values were more increased by the addition of resistant starch to the alginate formulation. The highest encapsulation efficiency was obtained with Alg-RS microparticles prepared using initial nisin to alginate weight ratio of 25% w/w (59.77 ± 2.26%). Fourier transform-infrared (FT-IR) spectroscopy, X-ray diffraction (XRD) and differential scanning calorimetry (DSC) results confirmed the presence of nisin in the microparticles. The in vitro nisin release from these microparticles followed a controlled-release pattern consistent with a Fickian diffusion mechanism. The release rate from Alg-RS microparticles was less than that from the Alg microparticles.
KW - Alginate
KW - Microparticle
KW - Nisin
KW - Resistant starch
UR - http://www.scopus.com/inward/record.url?scp=84893184088&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84893184088&partnerID=8YFLogxK
U2 - 10.1016/j.carbpol.2013.12.078
DO - 10.1016/j.carbpol.2013.12.078
M3 - Article
AN - SCOPUS:84893184088
VL - 103
SP - 573
EP - 580
JO - Carbohydrate Polymers
JF - Carbohydrate Polymers
SN - 0144-8617
IS - 1
ER -