TY - JOUR
T1 - Prenatal and perinatal risk factors for autism in China
AU - Zhang, Xin
AU - Lv, Cong Chao
AU - Tian, Jiang
AU - Miao, Ru Juan
AU - Xi, Wei
AU - Hertz-Picciotto, Irva
AU - Qi, Lihong
PY - 2010/11
Y1 - 2010/11
N2 - We conducted a case-control study using 190 Han children with and without autism to investigate prenatal and perinatal risk factors for autism in China. Cases were recruited through public special education schools and controls from regular public schools in the same region (Tianjin), with frequency matching on sex and birth year. Unadjusted analyses identified seven prenatal and seven perinatal risk factors significantly associated with autism. In the adjusted analysis, nine risk factors showed significant association with autism: maternal second-hand smoke exposure, maternal chronic or acute medical conditions unrelated to pregnancy, maternal unhappy emotional state, gestational complications, edema, abnormal gestational age (<35 or >42 weeks), nuchal cord, gravidity >1, and advanced paternal age at delivery (>30 year-old).
AB - We conducted a case-control study using 190 Han children with and without autism to investigate prenatal and perinatal risk factors for autism in China. Cases were recruited through public special education schools and controls from regular public schools in the same region (Tianjin), with frequency matching on sex and birth year. Unadjusted analyses identified seven prenatal and seven perinatal risk factors significantly associated with autism. In the adjusted analysis, nine risk factors showed significant association with autism: maternal second-hand smoke exposure, maternal chronic or acute medical conditions unrelated to pregnancy, maternal unhappy emotional state, gestational complications, edema, abnormal gestational age (<35 or >42 weeks), nuchal cord, gravidity >1, and advanced paternal age at delivery (>30 year-old).
KW - Autism
KW - China
KW - Perinatal
KW - Prenatal
KW - Risk factors
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U2 - 10.1007/s10803-010-0992-0
DO - 10.1007/s10803-010-0992-0
M3 - Article
C2 - 20358271
AN - SCOPUS:78549284561
VL - 40
SP - 1311
EP - 1321
JO - Journal of Autism and Developmental Disorders
JF - Journal of Autism and Developmental Disorders
SN - 0162-3257
IS - 11
ER -