Preliminary X-ray analysis of crystals of murine adenosine deaminase

David K. Wilson, Frederick B. Rudolph, Mary L. Harrison, Rodney E. Kellems, Florante A. Quiocho

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

We have obtained single crystals of a cloned mammalian adenosine deaminase (Mr = 41,000), a key enzyme in purine degradation and in normal development of the immune system, that are suitable for high-resolution structural analysis. The crystals belong to the space group C2 with unit cell parameters a = 101.68 A ̊ (1 A ̊ = 0.1 nm), b = 94.38 A ̊, c = 85.51 A ̊, and β = 96.54 °. The asymmetric unit contains two enzyme molecules.

Original languageEnglish (US)
Pages (from-to)613-614
Number of pages2
JournalJournal of Molecular Biology
Volume200
Issue number3
DOIs
StatePublished - Apr 5 1988
Externally publishedYes

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Adenosine Deaminase
X-Rays
Enzymes
Immune System
purine

ASJC Scopus subject areas

  • Virology

Cite this

Wilson, D. K., Rudolph, F. B., Harrison, M. L., Kellems, R. E., & Quiocho, F. A. (1988). Preliminary X-ray analysis of crystals of murine adenosine deaminase. Journal of Molecular Biology, 200(3), 613-614. https://doi.org/10.1016/0022-2836(88)90549-9

Preliminary X-ray analysis of crystals of murine adenosine deaminase. / Wilson, David K.; Rudolph, Frederick B.; Harrison, Mary L.; Kellems, Rodney E.; Quiocho, Florante A.

In: Journal of Molecular Biology, Vol. 200, No. 3, 05.04.1988, p. 613-614.

Research output: Contribution to journalArticle

Wilson, DK, Rudolph, FB, Harrison, ML, Kellems, RE & Quiocho, FA 1988, 'Preliminary X-ray analysis of crystals of murine adenosine deaminase', Journal of Molecular Biology, vol. 200, no. 3, pp. 613-614. https://doi.org/10.1016/0022-2836(88)90549-9
Wilson, David K. ; Rudolph, Frederick B. ; Harrison, Mary L. ; Kellems, Rodney E. ; Quiocho, Florante A. / Preliminary X-ray analysis of crystals of murine adenosine deaminase. In: Journal of Molecular Biology. 1988 ; Vol. 200, No. 3. pp. 613-614.
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