Preliminary X-ray analysis of crystals of murine adenosine deaminase

David K. Wilson, Frederick B. Rudolph, Mary L. Harrison, Rodney E. Kellems, Florante A. Quiocho

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

We have obtained single crystals of a cloned mammalian adenosine deaminase (Mr = 41,000), a key enzyme in purine degradation and in normal development of the immune system, that are suitable for high-resolution structural analysis. The crystals belong to the space group C2 with unit cell parameters a = 101.68 A ̊ (1 A ̊ = 0.1 nm), b = 94.38 A ̊, c = 85.51 A ̊, and β = 96.54 °. The asymmetric unit contains two enzyme molecules.

Original languageEnglish (US)
Pages (from-to)613-614
Number of pages2
JournalJournal of Molecular Biology
Volume200
Issue number3
DOIs
StatePublished - Apr 5 1988
Externally publishedYes

ASJC Scopus subject areas

  • Virology

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    Wilson, D. K., Rudolph, F. B., Harrison, M. L., Kellems, R. E., & Quiocho, F. A. (1988). Preliminary X-ray analysis of crystals of murine adenosine deaminase. Journal of Molecular Biology, 200(3), 613-614. https://doi.org/10.1016/0022-2836(88)90549-9