Abstract
90Y and 111In have been attached to chimeric monoclonal antibody L6 with a bifunctional chelating agent (DOTA-peptide isothiocyanate). The bifunctional chelating agent was prelabeled with either radiometal and then conjugated to the antibody. Studies in human patients showed excellent 111In single-photon emission computed tomography images of breast cancer lesions 24 h after injection.
Original language | English (US) |
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Journal | Cancer Research |
Volume | 55 |
Issue number | 23 SUPPL. |
State | Published - 1995 |
ASJC Scopus subject areas
- Cancer Research
- Oncology