Ten women who had had the idiopathic nephrotic syndrome but who had been in remission from 8 months to 19 years (mean 8.42 years) prior to the onset of pregnancy were studied during pregnancy. Seven of ten had no problems pertaining to their previous renal disease. One patient had an overt relapse of the nephrotic syndrome, another had aggravation of proteinuria only, and another developed mild azotemia with aggravation of proteinuria. A total of 18 pregnancies were observed; of these 17 resulted in the births of live newborn babies. Only one infant had a congenital malformation. It is suggested that pregnancy in patients who are in remission of the nephrotic syndrome usually does not lead to reactivation of the nephrotic syndrome in the mother and probably does not carry an increased risk of fetal illness and death.
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health