Pregnancy-associated cervical cancer: Obstetric outcomes

John L. Dalrymple, William M. Gilbert, Gary S Leiserowitz, Rosemary D Cress, Guibo Xing, Beate Danielsen, Lloyd H Smith

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


Objective. Describe the obstetric outcomes among women in California with pregnancy associated cervical cancer. Methods. Cases were identified utilizing computer-linked infant birth/death certificates, discharge records, and cancer registry files, and then assigned to a prenatal or post-partum cancer diagnosis group. Outcomes included cesarean delivery, hospitalizations, birth weight, prematurity, and infant mortality. Results. Among 434 cases identified, those diagnosed prenatally (136 cases) had higher rates of cesarean section (odds ratio 3.7; 95% CI 2.6, 5.2), hospitalization > 5 days (maternal: odds ratio 14.1; 95% CI 9.2, 21.5 neonatal: odds ratio 5.2; 95% CI 3.6, 7.5), low birth weight (LBW) (odds ratio 5.5; 95% CI 3.7, 8.1), very LBW (odds ratio 6.9; 95% CI 3.7, 12.8), prematurity (odds ratio 4.7; 95% CI 3.2, 6.7), and fetal deaths (odds ratio 5.5; 95% CI 2.0, 14.8) compared to non-cancer pregnant controls. Very LBW (odds ratio 2.6; 95% CI 1.4, 4.8), prematurity (odds ratio 1.5; 95% CI 1.1, 2.1), and fetal death rates (odds ratio 3.0; 95% CI 1.2, 7.4) remained elevated among those diagnosed post-partum. No neonatal deaths were attributable to elective premature delivery. Conclusions. We observed higher rates of fetal death and spontaneous prematurity among women with pregnancy-associated cervical cancer.

Original languageEnglish (US)
Pages (from-to)269-276
Number of pages8
JournalJournal of Maternal-Fetal and Neonatal Medicine
Issue number4
StatePublished - Apr 2005


  • Cervical cancer
  • Obstetric outcomes
  • Pregnancy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology


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