Predictors of symptomatic urinary tract infection after 20 weeks' gestation

Lisa M. Pastore, David A. Savitz, John M. Thorp, Gary G. Koch, Irva Hertz-Picciotto, Debra E. Irwin

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

OBJECTIVE: To identify predictors of symptomatic urinary tract infection (UTI) after 20 weeks' gestation. STUDY DESIGN: A retrospective cohort analysis was conducted of all deliveries at three North Carolina hospitals between 1990 and 1993. A total of 7403 deliveries remained after exclusions (pre-pregnancy diabetes, HIV-positive, structural urologic abnormalities, no prenatal care) and restrictions (black or white race, county of residence). Cystitis and pyelonephritis were identified by clinician diagnosis. Multiple logistic regression was conducted. RESULTS: Prior UTIs (both before and earlier in pregnancy), nonprivale clinics, and a history of chlamydia (white women only) doubled the risk of symptomatic UTIs after 20 weeks' gestation. The strongest predictor of pyelonephritis was prior antenatal UTIs (adjusted incidence odds ratio = 5.3,95% confidence interval of 2.6-11.0), followed by less education (<12 years), a history of chlamydia, nonprivate clinics, illicit drug use, sickle cell hemoglobinopathy, and being unmarried. CONCLUSION: Medical history and demographic factors predict cystitis and pyelonephritis after 20 weeks' gestation. Prospective studies of pyelonephritis predictors and screening strategies are warranted.

Original languageEnglish (US)
Pages (from-to)488-493
Number of pages6
JournalJournal of Perinatology
Volume19
Issue number7
StatePublished - Oct 1999
Externally publishedYes

Fingerprint

Urinary Tract Infections
Pyelonephritis
Pregnancy
Cystitis
Chlamydia
Hemoglobinopathies
Prenatal Care
Street Drugs
Cohort Studies
Logistic Models
Odds Ratio
Demography
HIV
Prospective Studies
Confidence Intervals
Education
Incidence

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Pediatrics, Perinatology, and Child Health

Cite this

Pastore, L. M., Savitz, D. A., Thorp, J. M., Koch, G. G., Hertz-Picciotto, I., & Irwin, D. E. (1999). Predictors of symptomatic urinary tract infection after 20 weeks' gestation. Journal of Perinatology, 19(7), 488-493.

Predictors of symptomatic urinary tract infection after 20 weeks' gestation. / Pastore, Lisa M.; Savitz, David A.; Thorp, John M.; Koch, Gary G.; Hertz-Picciotto, Irva; Irwin, Debra E.

In: Journal of Perinatology, Vol. 19, No. 7, 10.1999, p. 488-493.

Research output: Contribution to journalArticle

Pastore, LM, Savitz, DA, Thorp, JM, Koch, GG, Hertz-Picciotto, I & Irwin, DE 1999, 'Predictors of symptomatic urinary tract infection after 20 weeks' gestation', Journal of Perinatology, vol. 19, no. 7, pp. 488-493.
Pastore LM, Savitz DA, Thorp JM, Koch GG, Hertz-Picciotto I, Irwin DE. Predictors of symptomatic urinary tract infection after 20 weeks' gestation. Journal of Perinatology. 1999 Oct;19(7):488-493.
Pastore, Lisa M. ; Savitz, David A. ; Thorp, John M. ; Koch, Gary G. ; Hertz-Picciotto, Irva ; Irwin, Debra E. / Predictors of symptomatic urinary tract infection after 20 weeks' gestation. In: Journal of Perinatology. 1999 ; Vol. 19, No. 7. pp. 488-493.
@article{f60173b4565942a3b10615359c900aa0,
title = "Predictors of symptomatic urinary tract infection after 20 weeks' gestation",
abstract = "OBJECTIVE: To identify predictors of symptomatic urinary tract infection (UTI) after 20 weeks' gestation. STUDY DESIGN: A retrospective cohort analysis was conducted of all deliveries at three North Carolina hospitals between 1990 and 1993. A total of 7403 deliveries remained after exclusions (pre-pregnancy diabetes, HIV-positive, structural urologic abnormalities, no prenatal care) and restrictions (black or white race, county of residence). Cystitis and pyelonephritis were identified by clinician diagnosis. Multiple logistic regression was conducted. RESULTS: Prior UTIs (both before and earlier in pregnancy), nonprivale clinics, and a history of chlamydia (white women only) doubled the risk of symptomatic UTIs after 20 weeks' gestation. The strongest predictor of pyelonephritis was prior antenatal UTIs (adjusted incidence odds ratio = 5.3,95{\%} confidence interval of 2.6-11.0), followed by less education (<12 years), a history of chlamydia, nonprivate clinics, illicit drug use, sickle cell hemoglobinopathy, and being unmarried. CONCLUSION: Medical history and demographic factors predict cystitis and pyelonephritis after 20 weeks' gestation. Prospective studies of pyelonephritis predictors and screening strategies are warranted.",
author = "Pastore, {Lisa M.} and Savitz, {David A.} and Thorp, {John M.} and Koch, {Gary G.} and Irva Hertz-Picciotto and Irwin, {Debra E.}",
year = "1999",
month = "10",
language = "English (US)",
volume = "19",
pages = "488--493",
journal = "Journal of Perinatology",
issn = "0743-8346",
publisher = "Nature Publishing Group",
number = "7",

}

TY - JOUR

T1 - Predictors of symptomatic urinary tract infection after 20 weeks' gestation

AU - Pastore, Lisa M.

AU - Savitz, David A.

AU - Thorp, John M.

AU - Koch, Gary G.

AU - Hertz-Picciotto, Irva

AU - Irwin, Debra E.

PY - 1999/10

Y1 - 1999/10

N2 - OBJECTIVE: To identify predictors of symptomatic urinary tract infection (UTI) after 20 weeks' gestation. STUDY DESIGN: A retrospective cohort analysis was conducted of all deliveries at three North Carolina hospitals between 1990 and 1993. A total of 7403 deliveries remained after exclusions (pre-pregnancy diabetes, HIV-positive, structural urologic abnormalities, no prenatal care) and restrictions (black or white race, county of residence). Cystitis and pyelonephritis were identified by clinician diagnosis. Multiple logistic regression was conducted. RESULTS: Prior UTIs (both before and earlier in pregnancy), nonprivale clinics, and a history of chlamydia (white women only) doubled the risk of symptomatic UTIs after 20 weeks' gestation. The strongest predictor of pyelonephritis was prior antenatal UTIs (adjusted incidence odds ratio = 5.3,95% confidence interval of 2.6-11.0), followed by less education (<12 years), a history of chlamydia, nonprivate clinics, illicit drug use, sickle cell hemoglobinopathy, and being unmarried. CONCLUSION: Medical history and demographic factors predict cystitis and pyelonephritis after 20 weeks' gestation. Prospective studies of pyelonephritis predictors and screening strategies are warranted.

AB - OBJECTIVE: To identify predictors of symptomatic urinary tract infection (UTI) after 20 weeks' gestation. STUDY DESIGN: A retrospective cohort analysis was conducted of all deliveries at three North Carolina hospitals between 1990 and 1993. A total of 7403 deliveries remained after exclusions (pre-pregnancy diabetes, HIV-positive, structural urologic abnormalities, no prenatal care) and restrictions (black or white race, county of residence). Cystitis and pyelonephritis were identified by clinician diagnosis. Multiple logistic regression was conducted. RESULTS: Prior UTIs (both before and earlier in pregnancy), nonprivale clinics, and a history of chlamydia (white women only) doubled the risk of symptomatic UTIs after 20 weeks' gestation. The strongest predictor of pyelonephritis was prior antenatal UTIs (adjusted incidence odds ratio = 5.3,95% confidence interval of 2.6-11.0), followed by less education (<12 years), a history of chlamydia, nonprivate clinics, illicit drug use, sickle cell hemoglobinopathy, and being unmarried. CONCLUSION: Medical history and demographic factors predict cystitis and pyelonephritis after 20 weeks' gestation. Prospective studies of pyelonephritis predictors and screening strategies are warranted.

UR - http://www.scopus.com/inward/record.url?scp=0033202092&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033202092&partnerID=8YFLogxK

M3 - Article

C2 - 10685296

AN - SCOPUS:0033202092

VL - 19

SP - 488

EP - 493

JO - Journal of Perinatology

JF - Journal of Perinatology

SN - 0743-8346

IS - 7

ER -