Abstract
The most effective therapy for patients with stage A, grade II through III transitional cell carcinoma of the bladder is cystectomy. However, as only 40% of these tumors progress, 60% of the patients will be over-treated. This paper review the ability of the red cell adherence test, karyotyping, and DNA/RNA histograms to identify the 40% of tumors that will progress. All of these tests have their limitations. However, if patients with stage A, grade II-III, AB0 negative aneuploid positive tumors were subjected to cystectomy, the extent of the over-treated group would be substantially reduced.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 73-75 |
| Number of pages | 3 |
| Journal | World Journal of Urology |
| Volume | 3 |
| Issue number | 2 |
| DOIs | |
| State | Published - Sep 1985 |
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ASJC Scopus subject areas
- Urology
Cite this
Predicting the invasive potential of bladder carcinoma. / deVere White, Ralph W; Cockburn, Alden G.
In: World Journal of Urology, Vol. 3, No. 2, 09.1985, p. 73-75.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Predicting the invasive potential of bladder carcinoma
AU - deVere White, Ralph W
AU - Cockburn, Alden G.
PY - 1985/9
Y1 - 1985/9
N2 - The most effective therapy for patients with stage A, grade II through III transitional cell carcinoma of the bladder is cystectomy. However, as only 40% of these tumors progress, 60% of the patients will be over-treated. This paper review the ability of the red cell adherence test, karyotyping, and DNA/RNA histograms to identify the 40% of tumors that will progress. All of these tests have their limitations. However, if patients with stage A, grade II-III, AB0 negative aneuploid positive tumors were subjected to cystectomy, the extent of the over-treated group would be substantially reduced.
AB - The most effective therapy for patients with stage A, grade II through III transitional cell carcinoma of the bladder is cystectomy. However, as only 40% of these tumors progress, 60% of the patients will be over-treated. This paper review the ability of the red cell adherence test, karyotyping, and DNA/RNA histograms to identify the 40% of tumors that will progress. All of these tests have their limitations. However, if patients with stage A, grade II-III, AB0 negative aneuploid positive tumors were subjected to cystectomy, the extent of the over-treated group would be substantially reduced.
UR - http://www.scopus.com/inward/record.url?scp=0022258411&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0022258411&partnerID=8YFLogxK
U2 - 10.1007/BF00326712
DO - 10.1007/BF00326712
M3 - Article
AN - SCOPUS:0022258411
VL - 3
SP - 73
EP - 75
JO - World Journal of Urology
JF - World Journal of Urology
SN - 0724-4983
IS - 2
ER -