Predicting the invasive potential of bladder carcinoma

Ralph W deVere White, Alden G. Cockburn

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


The most effective therapy for patients with stage A, grade II through III transitional cell carcinoma of the bladder is cystectomy. However, as only 40% of these tumors progress, 60% of the patients will be over-treated. This paper review the ability of the red cell adherence test, karyotyping, and DNA/RNA histograms to identify the 40% of tumors that will progress. All of these tests have their limitations. However, if patients with stage A, grade II-III, AB0 negative aneuploid positive tumors were subjected to cystectomy, the extent of the over-treated group would be substantially reduced.

Original languageEnglish (US)
Pages (from-to)73-75
Number of pages3
JournalWorld Journal of Urology
Issue number2
StatePublished - Sep 1985

ASJC Scopus subject areas

  • Urology


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