Pradofloxacin

A novel veterinary fluoroquinolone for treatment of bacterial infections in cats

Jane E Sykes, Joseph M. Blondeau

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Pradofloxacin is a novel third-generation oral veterinary fluoroquinolone with activity against Gram-positive aerobic bacteria and anaerobes (lower minimum inhibitory concentrations in vitro). It also has activity against other bacterial species, including Bartonella henselae, Pasteurella multocida, Bordetella bronchiseptica, extra-intestinal Escherichia coli, and some mycobacterial species. This review focuses on the current knowledge of the mechanism of action, adverse effects, clinical applications, and pharmacokinetic/pharmacodynamic properties of pradofloxacin in cats.

Original languageEnglish (US)
Pages (from-to)207-214
Number of pages8
JournalVeterinary Journal
Volume201
Issue number2
DOIs
StatePublished - 2014

Fingerprint

Bartonella henselae
Bordetella bronchiseptica
fluoroquinolones
anaerobes
Fluoroquinolones
Pasteurella multocida
pharmacology
minimum inhibitory concentration
bacterial infections
Bacterial Infections
pharmacokinetics
mouth
mechanism of action
Cats
adverse effects
cats
Escherichia coli
Aerobic Bacteria
bacteria
Gram-Positive Bacteria

Keywords

  • Antimicrobial
  • Minimum inhibitory concentration
  • Pharmacodynamics
  • Pharmacokinetics
  • Resistance

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Pradofloxacin : A novel veterinary fluoroquinolone for treatment of bacterial infections in cats. / Sykes, Jane E; Blondeau, Joseph M.

In: Veterinary Journal, Vol. 201, No. 2, 2014, p. 207-214.

Research output: Contribution to journalArticle

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