Pradofloxacin: A novel veterinary fluoroquinolone for treatment of bacterial infections in cats

Jane E Sykes, Joseph M. Blondeau

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Pradofloxacin is a novel third-generation oral veterinary fluoroquinolone with activity against Gram-positive aerobic bacteria and anaerobes (lower minimum inhibitory concentrations in vitro). It also has activity against other bacterial species, including Bartonella henselae, Pasteurella multocida, Bordetella bronchiseptica, extra-intestinal Escherichia coli, and some mycobacterial species. This review focuses on the current knowledge of the mechanism of action, adverse effects, clinical applications, and pharmacokinetic/pharmacodynamic properties of pradofloxacin in cats.

Original languageEnglish (US)
Pages (from-to)207-214
Number of pages8
JournalVeterinary Journal
Volume201
Issue number2
DOIs
StatePublished - 2014

Keywords

  • Antimicrobial
  • Minimum inhibitory concentration
  • Pharmacodynamics
  • Pharmacokinetics
  • Resistance

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

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