Abstract
Type H1 horizontal cells depolarize when either L-glutamate or L-aspartate is added at millimolar concentrations to Ringer superfused over the photoreceptor side of the isolated goldfish retina. When applied in the presence of D-aspartate, however, L-glutamate depolarizes H1 cells at nearly 15-fold lower concentrations. Despite the fact that L-aspartate and L-glutamate are equally capable of producing depolarizations of H1 cells when applied alone, the effects of L-aspartateare not potentiated by either D-aspartate or D-glutamate. Since D-aspartate seems also to enhance the effect of neurotransmitter released by cone photoreceptors, these results are consistent with the possibility that L-glutamate is released by cones as a neurotransmitters.
Original language | English (US) |
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Pages (from-to) | 35-39 |
Number of pages | 5 |
Journal | Biomedical Research |
Volume | 3 |
Issue number | Suppl. |
State | Published - 1982 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)