Potenzial der MRT für die radiofrequenzablation von lebertumoren

Translated title of the contribution: Potential advantages of the MRI for the radiofrequency ablation of liver tumors

Gunnar Gaffke, B. Gebauer, M. Gnauck, Friedrich D Knollmann, T. Helmberger, J. Ricke, H. Oettle, R. Felix, C. Stroszczynski

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Purpose: To present first results of radiofrequency ablation of liver tumors using a new MR compatible applicator. Materials and Methods: We performed 37 interventions in 20 patients (mean age 58.6 years) with primary intrahepatic malignancies or metastases: colorectal carcinoma n = 6, hepatocellular carcinoma n = 3, pancreatic carcinoma n = 4, sarcoma n = 2, cholangiocellular carcinoma n = 1, carcinoma of the tonsil n = 1, breast carcinoma n = 1, gastric carcinoma n = 1, and gastrointestinal stroma tumor n = 1. Interventions were performed under CT-guidance with CT fluoroscopy (n = 32) and under MR-guidance (n = 5) using fast T1-weighted sequences in breath-hold technique. RFA was performed with the RF-generator (150 W) under local anesthesia and sedation using MR compatible applicators (Starburst XL, Rita Medical Systems, USA) together with the appropriate Soft Tissue Introducer System. Intra-interventional control was performed with intrahepatically or intralesionally placed introducer system or applicator. MRI was performed with plain breath-triggered T2-weighted turbo spin echo sequences (TSE T2) with fat saturation. Results: All interventions were performed without major events. The mean diameter of induced coagulation was 4.0 (± 0.7) cm. Repositioning was necessary in 8 interventions (21%) after detection of residual tumor on an intra-interventional MRI. After a mean follow-up of 6.5 (± 1.2) months, the local tumor control rate was 92%. Conclusion: MR-compatible RF applicators offer the opportunity for intra-interventional detection of residual tumor during RF ablations by use of sensitive MRI sequences. These procedures may lead to a higher confidence in tumour ablation and may reduce the number of re-interventions and local recurrences of intrahepatic tumors.

Translated title of the contributionPotential advantages of the MRI for the radiofrequency ablation of liver tumors
Original languageGerman
Pages (from-to)77-83
Number of pages7
JournalRoFo Fortschritte auf dem Gebiet der Rontgenstrahlen und der Bildgebenden Verfahren
Volume177
Issue number1
DOIs
StatePublished - Jan 2005
Externally publishedYes

Keywords

  • Interventional MR
  • Liver
  • Liver neoplasms
  • MR
  • Radiofrequency ablation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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