Potency and efficacy of inactivated bluetongue virus vaccines.

D. R. Stevens; J. Stott; B. I. Osburn; R. Giles; G. P. Wiesehahn; T. L. Barber

Potency and efficacy of inactivated bluetongue virus vaccines.

D. R. Stevens, J. Stott, B. I. Osburn, R. Giles, G. P. Wiesehahn, T. L. Barber

School of Veterinary Medicine

Research output: Contribution to journal › Article

6 Scopus citations

Abstract

Bluetongue virus (BTV) was chemically inactivated and was shown to elicit neutralizing antibodies in vaccinated rabbits and sheep. In sheep, the neutralizing antibody was shown to be protective by immunity challenge with virulent virus. These studies have shown the feasibility of safe and effective inactivated vaccines for bluetongue (BT) disease of sheep.

Original language	English (US)
Pages (from-to)	649-652
Number of pages	4
Journal	Progress in Clinical and Biological Research
Volume	178
State	Published - 1985

ASJC Scopus subject areas

Medicine(all)

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Stevens, D. R., Stott, J., Osburn, B. I., Giles, R., Wiesehahn, G. P., & Barber, T. L. (1985). Potency and efficacy of inactivated bluetongue virus vaccines. Progress in Clinical and Biological Research, 178, 649-652.

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abstract = "Bluetongue virus (BTV) was chemically inactivated and was shown to elicit neutralizing antibodies in vaccinated rabbits and sheep. In sheep, the neutralizing antibody was shown to be protective by immunity challenge with virulent virus. These studies have shown the feasibility of safe and effective inactivated vaccines for bluetongue (BT) disease of sheep.",

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AU - Stevens, D. R.

AU - Stott, J.

AU - Osburn, B. I.

AU - Giles, R.

AU - Wiesehahn, G. P.

AU - Barber, T. L.

PY - 1985

Y1 - 1985

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AB - Bluetongue virus (BTV) was chemically inactivated and was shown to elicit neutralizing antibodies in vaccinated rabbits and sheep. In sheep, the neutralizing antibody was shown to be protective by immunity challenge with virulent virus. These studies have shown the feasibility of safe and effective inactivated vaccines for bluetongue (BT) disease of sheep.

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