Postural and neurological deficits in broiler chicks after cervical vaccination with live vaccine

C. R. Gustafson, G. L. Cooper, B. R. Charlton, A. A. Bickford, R. Nordhausen

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A disease characterized by paresis and paralysis was seen in 7-9-day-old broiler chicks after vaccination in the neck area at day-of-age with a live virus vaccine containing viruses of Marek's disease, fowl pox, and infectious bursal disease. Affected birds presented with variable signs of ataxia, lateral recumbency, leg paralysis, and twisting or S-shaped flexure of the neck. Gross lesions noted at necropsy included swelling and edema of the subcutaneous tissues and muscles of the neck at the injection site area. A heavy mononuclear inflammatory cell infiltration was seen in the subcutaneous tissues, connective tissues, and muscles of the neck at the injection site. In some cases, the inflammatory process extended along fascial planes to involve the epidural spaces surrounding the spinal cord. Fatty changes with possible demyelination of nerve fibers were noted in some sections of the spinal cord adjacent to the inflammatory lesions. Clusters of poxviruses were found within some inflammatory lesions on transmission electron photomicrographs.

Original languageEnglish (US)
Pages (from-to)361-364
Number of pages4
JournalJournal of Veterinary Diagnostic Investigation
Volume15
Issue number4
StatePublished - Jul 2003

Fingerprint

Neck Muscles
Subcutaneous Tissue
live vaccines
neck
Spinal Cord
Fowlpox
Vaccination
Neck
Vaccines
broiler chickens
vaccination
lesions (animal)
Marek Disease
Poxviridae
Epidural Space
Injections
injection site
Paraplegia
Demyelinating Diseases
Paresis

ASJC Scopus subject areas

  • Microbiology
  • veterinary(all)

Cite this

Gustafson, C. R., Cooper, G. L., Charlton, B. R., Bickford, A. A., & Nordhausen, R. (2003). Postural and neurological deficits in broiler chicks after cervical vaccination with live vaccine. Journal of Veterinary Diagnostic Investigation, 15(4), 361-364.

Postural and neurological deficits in broiler chicks after cervical vaccination with live vaccine. / Gustafson, C. R.; Cooper, G. L.; Charlton, B. R.; Bickford, A. A.; Nordhausen, R.

In: Journal of Veterinary Diagnostic Investigation, Vol. 15, No. 4, 07.2003, p. 361-364.

Research output: Contribution to journalArticle

Gustafson, CR, Cooper, GL, Charlton, BR, Bickford, AA & Nordhausen, R 2003, 'Postural and neurological deficits in broiler chicks after cervical vaccination with live vaccine', Journal of Veterinary Diagnostic Investigation, vol. 15, no. 4, pp. 361-364.
Gustafson, C. R. ; Cooper, G. L. ; Charlton, B. R. ; Bickford, A. A. ; Nordhausen, R. / Postural and neurological deficits in broiler chicks after cervical vaccination with live vaccine. In: Journal of Veterinary Diagnostic Investigation. 2003 ; Vol. 15, No. 4. pp. 361-364.
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