Postmortem findings in patient with Guillain-Barré syndrome and zika virus infection

Emilio Dirlikov, José V. Torres, Roosecelis Brasil Martines, Sarah Reagan-Steiner, George Venero Pérez, Aidsa Rivera, Chelsea Major, Desiree Matos, Jorge Muñoz-Jordan, Wun Ju Shieh, Sherif R. Zaki, Tyler M. Sharp

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Postmortem examination results of a patient with Guillain-Barré syndrome and confirmed Zika virus infection revealed demyelination of the sciatic and cranial IV nerves, providing evidence of the acute demyelinating inflammatory polyneuropathy Guillain-Barré syndrome variant. Lack of evidence of Zika virus in nervous tissue suggests that pathophysiology was antibody mediated without neurotropism.

Original languageEnglish (US)
Pages (from-to)114-117
Number of pages4
JournalEmerging infectious diseases
Volume24
Issue number1
DOIs
StatePublished - Jan 2018
Externally publishedYes

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

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    Dirlikov, E., Torres, J. V., Martines, R. B., Reagan-Steiner, S., Pérez, G. V., Rivera, A., Major, C., Matos, D., Muñoz-Jordan, J., Shieh, W. J., Zaki, S. R., & Sharp, T. M. (2018). Postmortem findings in patient with Guillain-Barré syndrome and zika virus infection. Emerging infectious diseases, 24(1), 114-117. https://doi.org/10.3201/eid2401.171331